scientists in hallway

Careers

While the proteins and molecules we study may be small, to work at SBP is to be a part of something big.

Working at SBP

With more than 1,000 employees across the country, we're a world-class research institute that’s still small enough to feel like home. We take pride in offering competitive salaries and benefits that provide flexibility for the diverse and changing needs of our employees. What’s more, we are located in science and technology hotbeds. They're remarkable cities that also just happen to be beautiful places to live.

Position
Degenerative Diseases Program: Diabetes Research - Kaufman Lab
Location
La Jolla
Research

The laboratory of Dr. Randal Kaufman at Sanford Burnham Prebys Medical Discovery Institute in La Jolla, California has an opening for a Postdoctoral Associate. The lab’s research is aimed at elucidating fundamental mechanisms that regulate protein folding and the cellular responses to the accumulation of unfolded protein within the endoplasmic reticulum.

Type 2 diabetes results when beta cells are pressured to produce elevated levels of insulin to compensate for systemic insulin resistance.  As a consequence, protein-folding events within the endoplasmic reticulum are disturbed and unfolded proteins accumulate that lead to beta cell death.  The successful candidate will study insulin synthesis and secretion in beta cells from mice that are genetically engineered to alter protein-folding capacity in the ER.

Requirements

Candidates for this position must have a PhD or MD.  Technical skills will include molecular and cellular biology, protein biochemistry, and murine genetics. A strong publication record, excellent communication skills and ability to work in a team are essential. A background in beta cell biology is preferred.  Experience in working with mice is preferred. This is a unique position to work on a high profile project that will have a direct impact on human medical care.

Interested applicants should submit a copy of their CV, contact information (email address and phone number) of three references, and a brief statement of research skills and interest to Dr. Randal Kaufman c/o Taryn Goode via the Apply button below.

Apply Share
See details
Position
Development, Aging, and Regeneration Program - Colas Lab
Location
La Jolla
Research

Directing differentiation of stem cells, endogenous cardiac progenitors or cardiac fibroblasts to create new muscle is an aspiration of regenerative medicine. To that end, it is crucial to comprehensively identify and characterize gene regulatory networks controlling cardiac cell fate. To date, less than 30 genes have been tested for their ability to induce cardiac reprogramming, showing only modest effects when overexpressed in fibroblasts. This project is to use high-throughput functional screening strategies in order to identify new determinants of cardiac cell fate and evaluate their role both in vitro and in adult models of cardiac regeneration.

The Colas lab is located at Sanford Burnham Prebys Medical Discovery Institute (La Jolla, California) which stands at the forefront of basic biomedical and translational science. The institute provides world-class facilities, including one of the 4 nationwide screening centers, and a cooperative environment, which promotes productive collaborations.

Recent Publications:
1 AR. Colas et al. 2016. Submitted to Cell Stem Cell
2 T. Cunningham, A Colas et al. 2015. Plos One
3 M. Mercola, A Colas et al. 2013. Cardiovascular Drug Discovery Circ Res
4 A. Colas et al. 2012. Genes and Development
5 W. McKeithan*, A. Colas* et al. 2012. Curr Protoc Stem Cell Biol

Requirements

Applicants must have a Ph.D or M.D, be highly motivated, and have a track record of accomplishments (i.e one or more first-authored publications).  Experience in one or more of the following areas is required: developmental biology, stem cell biology, mouse models and high-throughput screening.

To apply, please send a CV, a brief statement of your previous research expertise, and the contact information of three references via the Apply button below.

Apply Share
See details
Position
Prebys Center - Sergienko Lab
Location
La Jolla
Research

The Postdoctoral Associate will be responsible for conducting chemical biology research through development and use of biochemical and biophysical assays of novel biological targets from diverse classes and therapeutic areas. The work will be conducted at Prebys Center, the state-of-the art drug discovery Center at Sanford Burnham Prebys Medical Discovery Institute.

Duties and Responsibilities:

  • Independently designs and performs experiments and procedures with high degree of complexity, demonstrating increasing expertise with a wide range of techniques.
  • Demonstrates flexibility in adapting methods/skills according to evolving project priorities.
  • Provides independent experimental design and follow up planning, interpretation of results and evaluation of data.
  • Able to analyze and interpret data from different sources and draw relevant conclusions.
  • Demonstrates knowledge in specialized disciplines.
  • Presents results within lab, and at external meetings.
  • Accurately documents experiments in lab notebook.
  • Contributes to writing of reports and manuscripts, with increasing responsibility over time.
  • Works collaboratively across functions. Trains junior members of team as needed.
Requirements
  • A Ph.D. degree or equivalent in scientific discipline such as biology, chemistry, or pharmacology, is required.
  • A minimum of five years experience conducting discovery research or related laboratory research. Advanced knowledge of biochemistry, enzymology, enzyme kinetics and thermodynamics, protein chemistry or other areas of math-intensive quantitative biology is highly desired.
  • The ability to work independently, and simultaneously handle multiple projects.
  • Demonstrated ability to work in an interactive team, excellent verbal and written communication skills, strong organizational skills.

Qualified motivated individuals should submit their CV, in addition to the names, e-mail addresses, and telephone numbers of three references to Dr. Eduard Sergienko, Director, Assay Development, via the Apply button below. Please cc: jcolomb@SBPdiscovery.org.

Apply Share
See details
Position
Prebys Center - Bang Lab
Location
La Jolla
Research

The successful candidate will be primarily responsible for conducting research related to developing human induced pluripotent stem cell (hiPSC) based models for use in CNS safety evaluation for early drug discovery programs. The project will focus on developing and validating assays for CNS safety evaluation based on both normal and neurodegenerative disease patient-specific hiPSC derived neural cells, and will utilize drug-screening technologies, including high content imaging, and multi-electrode arrays. The position is at the Sanford Burnham Prebys Medical Discovery Institute in Dr. Anne Bang’s lab in the Conrad Prebys Center for Chemical Genomics, a state-of-the-art drug screening facility. The position is a 2-year appointment and will be co-mentored by a toxicologist at Takeda California, Inc, and provide opportunities to interface with Takeda’s CNS drug discovery unit.

Requirements

This position requires an M.D., or Ph.D., with up to 3 years of experience. The qualified applicant must have proven experience in one or more of the following areas: toxicology, neurobiology, electrophysiology, pharmacology, molecular biology, stem cell biology. Research experience with neurotoxicology or general toxicology, electrophysiology, human iPSC or ESC, or neurological disease models, are highly desirable.

Interested individuals should submit CV, cover letter, and the names, e-mail addresses, and telephone numbers of three references via the Apply button below.

Apply Share
See details
Position
Development, Aging, and Regeneration Program - Itkin-Ansari Lab
Location
La Jolla
Research

The laboratory of Dr. Pamela Itkin-Ansari at SBP in La Jolla, California has an opening for a Postdoctoral Associate. The lab’s research is aimed at elucidating fundamental mechanisms of beta cell homeostasis in human and murine islets. Current projects include islet development, protein folding, and endoplasmic reticulum stress. The successful candidate will study insulin synthesis and secretion in beta cells which are altered genetically or with drug treatments.

Requirements

Candidates must have a PhD or MD. Excellent communication and writing skills and the ability to work in a team are essential. This is a unique position to work on a high profile project that could have a direct impact on human medical care.  A background in beta cell biology is preferred. Technical skills will include strength in molecular and cellular biology, protein biochemistry, and working with mice.

Interested candidates should send an email with a summary of achievements and research interests, updated CV and contact information for 3 letters of reference to via the Apply button below.

Apply Share
See details
Position
Degenerative Diseases Program - Xu Lab
Location
La Jolla
Research

The laboratory of Dr. Huaxi Xu at Sanford Burnham Prebys Medical Discovery Institute in La Jolla, California has an opening for a highly motivated Postdoctoral Associate.

The Xu laboratory is recognized for its cutting-edge research in Alzheimer’s disease and age-related neurodegenerative diseases. Research efforts at the Xu laboratory are aimed to understand the molecular and cellular mechanisms underlying neuronal function/dysfunction and cell death in neurodegenerative diseases, including Alzheimer’s disease and Down Syndrome. The lab has a long-standing interest in the identification of new genes and molecular pathways involved in the pathophysiology of neurodegeneration. The postdoctoral associate will have the opportunity to work with a wide range of techniques including molecular/cellular biology, protein biochemistry, electrophysiology, imaging, neurochemistry, animal models of disease, synapse biology, stereotactic surgery, and behavioral neuroscience.

Requirements

Candidates for this position must have a PhD or MD/PhD degree in cell/molecular biology. Technical skills will include molecular and cellular biology, cell culture, biochemistry, microscopy. A strong work ethic, excellent communication skills and ability to work in a team are essential. Attention to detail and strong data analysis skills are essential. A background in neuroscience is required.  Experience in working with mice is preferred.

Interested applicants should submit a copy of their CV, contact information (email address and phone number) three references, and a brief statement of research skills and interest to: Dr. Huaxi Xu c/o Lisa-Marie Bellovich via the Apply button below.

Apply Share
See details
Position
Cancer Metabolism and Signaling Networks Program - Moscat Lab
Location
La Jolla
Research

One fully funded postdoctoral position is available to study the role of autophagy adaptors in the control of the transcriptional activity of key mediators of stromal function in cancer. The project is based on our recent publication in Cancer Cell (Duran et al., 2016) and will use mouse models and cell based studies and the interrogation of human cancer samples. This is part of an ongoing collaboration between the laboratories of Jorge Moscat and Maria T. Diaz-Meco.

These laboratories are part of the Cancer Metabolism and Signaling Networks Program, an essential piece of the vibrant Sanford Burnham Prebys NCI-designated Cancer Center.

Our goal is to unravel the mechanistic crosstalk between stromal, immune, and tumor cells, to identify potential new targets for innovative cancer therapies. Additional publications by our labs describing ongoing studies in this area have appeared in for example: Mol. Cell (2011, 2013), Cell Metab. (2006, 2011, 2014), Cell (2009, 2011, 2013), Cell Reports (2015, 2016), and Cancer Cell (2008, 2014, 2016).

Requirements

We are looking for highly motivated and enthusiastic individuals who are interested in this very competitive topic, and with expertise in studies related to transcriptional activity and epigenetics. Candidates must have a Ph.D. or M.D. degree and a publication record demonstrating expertise in this area.

Interested applicants should submit a single PDF file containing CV, a brief description of research accomplishments, interests, and career goals, and contact information (e-mail address and phone number) of three references via the Apply button below (cc: Ms. Sarah Forte at sforte@SBPdiscovery.org)

The position is available starting immediately, and offers a very competitive health and retirement package.

Apply Share
See details
Position
Cancer Metabolism and Signaling Networks Program - Diaz-Meco/Moscat Labs
Location
La Jolla
Research

One fully funded postdoctoral position is available to study the role of autophagy adaptors in the immune response in the tumor microenvironment, and the generation of resistances to cancer therapy. The project will use mouse models and cell based studies and the interrogation of human cancer samples. This is part of an ongoing collaboration between the laboratories of Drs. Jorge Moscat and Maria T. Diaz-Meco. These laboratories are part of the Cancer Metabolism and Signaling Networks Program, an essential piece of the vibrant Sanford Burnham Prebys NCI-designated Cancer Center.

Our goal is to unravel the mechanistic crosstalk between stromal, immune, and tumor cells, to identify potential new targets for innovative cancer therapies. Publications by our labs describing ongoing studies in this area have appeared in for example: Mol. Cell (2011, 2013), Cell Metab. (2006, 2011, 2014), Cell (2009, 2011, 2013), Cell Reports (2015, 2016), and Cancer Cell (2008, 2014, 2016).

Requirements

We are looking for highly motivated and enthusiastic individuals who are interested in this very competitive topic, and with expertise in immunology and experience with mouse models. Candidates must have a Ph.D. or M.D. degree and a publication record demonstrating expertise in this area. 

Interested applicants should submit a single PDF file containing CV, a brief description of research accomplishments, interests, and career goals, and contact information (e-mail address and phone number) of three references to Ms. Sarah Forte via the Apply button below.

Apply Share
See details
Position
Integrative Metabolism Program - Perera Lab
Location
Lake Nona
Research

A Postdoctoral Associate position is available to study non-coding RNAs (long noncoding RNA and microRNAs) regulation in prostate and skin cancer.  Several putative oncogenic and tumor suppressor non-coding RNAs have been identified in our laboratory and we will characterize these through in-vitro and in-vivo functional and analytical genomics studies. 

The prospective candidate will continue this study at the Lake Nona site of SBP located in Orlando, Florida.

Requirements

The Ph.D. and/or M.D.  Candidate must have a strong background in at least one of the following areas: tumor biology, cell biology, molecular biology, and/or transcriptional/post-transcriptional gene regulation/bioinformatics. Interested and qualified candidates should submit their CV, cover letter and list of references to Ms. Debbie McFadden via the Apply button below.

Apply Share
See details
Position
Integrative Metabolism Program: X-Ray Crystallography of Transcription Factors - Rastinejad Lab
Location
Lake Nona
Research

A Post-Doctoral Associate position is available in Dr. Rastinejad’s laboratory at the Sanford Burnham Prebys Medical Discovery Institute, in Lake Nona, Florida.  This position provides an exceptional opportunity to enhance the candidate’s past training in X-ray crystallography, biochemistry, molecular biology and/or cell biology.  The research training will emphasize protein expression through a variety of innovative methods, biochemical characterization of pure proteins, their crystallization and structure determination through modern macromolecular X-ray crystallography/diffraction methods.  Selected candidate will additionally become exposed to high throughput drug-screening efforts in which the laboratory collaborates wit the Conrad-Prebys Center for Chemical Genomics within the same Institute.
 
The transcription factors to be studied are nuclear hormone receptors and mammalian bHLH-PAS proteins.  Recent studies within Dr. Rastinejad’s laboratory have led to breakthroughs in the structural visualization of multi-domain transcription factors in a variety of functionally revealing complexes that include bound DNA, small-molecule ligands and coregulators.  The new projects will involve intensive protein biochemistry, crystal growth and structure calculation and refinement based on X-ray diffraction data.  The high-throughput screens will also be integrated throughout the structural biology training program, with the goal of identifying potent small-molecules that act as activators and inhibitors of transcription factors.

Requirements

Requires a Ph.D. degree in Biology, Biochemistry or related field. Candidates who have strong research experience in X-ray crystallography, protein purification and biochemical binding studies, molecular biology, and/or cell-biology are strongly preferred. Ideal candidate would be motivated, possess excellent written and oral communication skills and possess a strong desire and ability to work as a team in a collaborative environment.  Interested candidates should apply with full CV, statement of research interests and list of references via the Apply button below.

Apply Share
See details
Position
Human Genetics Program - Freeze Lab
Location
La Jolla
Research

A Postdoctoral position is immediately available at the Sanford Burnham Prebys Medical Discovery Institute (SBP) to study NGLY1 mutations that cause a recently discovered human neurological disease of protein N-de-glycosylation. The pathological mechanism is unknown. 

Our team combines cell biology, biochemistry, and human genetics in solve Congenital Disorders of Glycosylation (CDG) including NGLY1. Fundamental discoveries are aimed at translational applications that can benefit patients. 

The postdoc will drive the project to identify consequences of disrupted N-glycan cleavage from misfolded glycoproteins that are retro-translocated into the cytoplasm. Plans include a search for obligate substrates, alternate cleavage pathways, potential therapeutic molecules, and analysis of patient cells. Techniques include gene manipulation, glycan analysis, fluorescence methods, and proteomic analysis.

Close collaborations with other NGLY1 research laboratories, the NIH, and philanthropic organizations provide unique interactive opportunities for the candidate.

If interested in this challenging research opportunity in NGLY1, please read PMID: 24651605, PMID: 25900930, and www.newyorker.com/magazine/2014/07/21/one-of-a-kind-2

Requirements
  • Recent PhD or MD/PhD with strong motivation and background in biochemistry, genetics, cellular & molecular biology.
  • First-author publications in any 2 of the following: biochemistry, cell biology, glycobiology, gene manipulation, ERAD or cytoplasmic protein degradation.
  • Excellent verbal/written communication skills in fluent English.
  • Previous experience in a biochemistry, genetics, or cellular/molecular biology lab based in the United States.
  • Independent self-starter who thrives in a highly interactive, collaborative scientific environment.

How to Apply:
Send a single PDF document that includes all of the following:

  • Your current CV
  • 1 page letter outlining your background, specific interest in NGLY1, and how you would like to study it.
  • 3 recent reference contacts for this project.

Email the PDF document to Dr. Hudson Freeze via the Apply button below.

Apply Share
See details
Position
Immunity and Pathogenesis Program: Host-Pathogen Interactions and Neuroinflammation - Kaul Lab
Location
La Jolla
Research

A postdoctoral position is immediately available in the Infectious and Inflammatory Disease Center (IIDC) in the laboratory of Dr. Marcus Kaul in projects investigating i) cellular and molecular mechanisms of host-pathogen interaction that lead to neuroinflammation and degeneration and ii) innate neuroprotective factors. A major focus is the neurotoxicity and brain injury associated with HIV-1 infection. The positions will be integral parts of studies dissecting molecular mechanisms of inflammatory and innate immune signaling pathways in macrophages and neural cell types using in vitro and in vivo models. The projects will combine molecular, cellular, biochemical as well as bioinformatics-based approaches, including NextGen Sequencing, RNAi, ASO, knockout and transgenic mouse models, etc. The positions are supported by NIH funding. 

Requirements

Highly motivated candidates who recently obtained a Ph.D. and/or M.D. degree, with a strong background either in neurobiology or inflammation, innate immunology, molecular biology and virology and biochemistry are encouraged to apply. Experience with transgenic and knockout or humanized mouse models and cellular signaling is a plus. Candidates must have good communication skills, and should be able to work independently in a highly interactive and collaborative scientific environment. Successful candidates will have a solid publication record in peer-reviewed journals.

Interested individuals should send their curriculum vitae, a brief description of their scientific background and interests, and the names of three references via the Apply button below.

Apply Share
See details
Position
Immunity and Pathogenesis Program - Baaten Lab
Location
La Jolla
Research

A postdoctoral position is immediately available in the immunity and pathogenesis program at the Sanford Burnham Prebys Medical Discovery Institute to study host-pathogen interactions at mucosal surfaces. The selected candidate will lead our ongoing efforts to identify the mechanisms that govern the balance between immunity and pathology at the nasal and pulmonary mucosa following viral infection. Current projects are focused on exploring the mechanisms underlying defective T cell immunity in the aged following influenza virus infection. He/she will use an array of cellular and molecular approaches to evaluate immune function in mouse models and human cells and is expected to formulate, execute, and communicate research projects. 

Requirements

Highly motivated individuals with a strong background in cellular and molecular immunology and who recently obtained a Ph.D. are strongly encouraged to apply.  Previous experience with mouse models is highly desired. Candidates must have good communication skills, and should be able to work independently and in a collaborative scientific environment. 

Interested applicants should submit a CV, contact information (e-mail address and phone number) of three references, and a brief description of research accomplishments, interests, and career goals to Dr. Bas Baaten via the Apply button below.

Apply Share
See details
Position
Tumor Microenvironment and Cancer Immunology Program - Marth Lab
Location
Off Campus
Research

A postdoctoral position is available in the laboratory of Dr. Jamey Marth to study infectious diseases and the complication of sepsis.  The lab is focused upon how protein glycosylation and glycoprotein remodeling control the aging and turnover of secreted proteins in modulating the coagulopathy and inflammation of microbial sepsis.  The project will include both mouse models and human patients involving collaborations between scientists and clinicians. 

Requirements

Candidates must have a Ph.D. or M.D. in Molecular Biology, Microbiology, or Clinical Medicine. Ideal candidates would have experience in infectious disease research, inflammatory biology, protein biochemistry, and proteomics.  Training will be provided as necessary to include glycan linkage analyses. 

Interested candidates should send their CV and names of three personal references via the Apply button below or regular mail to:
Katelyn Jerlinga
9625 MCDB, University of California
Santa Barbara, CA 93106-9625

Apply Share
See details
Position
Tumor Initiation and Maintenance Program - Commisso Lab
Location
La Jolla
Research

The NCI-Designated Cancer Center of Sanford Burnham Prebys Medical Discovery Institute located in La Jolla, CA, is recruiting Postdoctoral Fellows to study cancer cell biology.

The Commisso Lab is focused on biological discoveries that have the potential to lead to novel therapeutic strategies for cancer. Of particular interest to our laboratory are Ras-driven cancers, such as tumors of the pancreas, colon and lung, which are extremely aggressive and are in urgent need of new and innovative therapies. The biological process that we study in the lab is called macropinocytosis, a fluid-phase form of bulk endocytic uptake, which we have linked to cancer cell metabolism in Ras-mutated tumors.

We are seeking highly motivated individuals to join our research team. The successful candidates will be active participants in a vibrant, collaborative atmosphere. The candidates will design and implement experiments using a variety of techniques such as cell culture, cell biology, molecular biology, and animal tumor models to help understand cancer cell dependencies at the molecular level. The main goal is to identify and develop novel therapeutic targets and to discover therapeutic agents to treat Ras-driven cancers.

Requirements

Experimental bench science is an essential requirement, as well as the ability to present and discuss data. A research background in cancer biology, cell biology, or cell signaling is required and prior experience with mouse models and microscopy is preferred.

Candidates must have a Ph.D. degree and demonstrate the ability to successfully spearhead a research project by having first author publications in reputable and high impact journals (published, submitted or soon to be submitted).

Interested applicants should submit a cover letter and a CV. The last page of the CV should include the contact information (e-mail address and phone number) for three references. The PDF files should be emailed to Dr. Cosimo Commisso via the Apply button below.

Apply Share
See details
Position
Cancer Metabolism and Signaling Networks Program - Emerling Lab
Location
La Jolla
Research

We are currently seeking highly motivated and independent postdocs to join the Emerling lab to investigate the role of the PI5P4K enzymes in cancer metabolism. Current work focuses on the requirement of the PI5P4K enzymes in breast cancer and autophagy using genetically engineered mouse models.

Requirements

Candidates should have a recent PhD or MD/PhD degree and experience in cancer metabolism and/or mouse tumor models. Additional experience in autophagy biology and cell signaling as well as with technologies including metabolomics is highly desirable. 
To apply, please send your CV, description of past research and list of three referees via the Apply button below.

Apply Share
See details
Position
Tumor Initiation and Maintenance Program - Pasquale Lab
Location
La Jolla
Research

Postdoctoral position in Eph receptor cancer biology.
A postdoctoral position is available to study the dual signaling mechanisms of Eph receptors in tumor promotion and tumor suppression, and the regulatory role of serine/threonine phosphorylation in Eph receptor function. The project will combine molecular, cellular, biochemical and proteomics approaches and in vivo mouse cancer models, and take advantage of interdisciplinary collaborations. 

The Pasquale laboratory is part of the NCI-Designated Cancer Center and has a longstanding track record in studying the Eph family of receptor tyrosine kinases. Current research in the laboratory focuses on elucidating Eph receptor signaling pathways relevant to cancer biology, characterizing the effects of Eph receptor cancer mutations, and developing new Eph receptor-targeting agents for cancer imaging/treatment and against neurodegenerative diseases.

Requirements

We are looking for a highly motivated, detail oriented and collaborative individual with a PhD or MD degree and a strong record of research productivity demonstrated through peer-reviewed publications. A background in molecular and cell biology and prior experience in signal transduction research are preferred. Interested applicants should submit a single PDF file that includes their CV, a brief description of research accomplishments, interests and career goals, and contact information of at least three references via the Apply button below.

Apply Share
See details
Position
Tumor Initiation and Maintenance Program - Adams Lab
Location
La Jolla
Research

Applications are invited from ambitious, independent and motivated candidates to work with Professor Peter D. Adams to investigate the epigenetics of aging and age-associated diseases, such as cancer. Specific projects range from development of novel epigenetic therapies to combat cancer (for example, epigenetic therapies to synergize with immune therapies), to mechanistic investigation of epigenetic control of cellular senescence and aging, particularly those events that pre-dispose to cancer. A long-term goal of the lab is to develop epigenetic-based therapies that can prevent age-associated events that predispose to cancer, with a view to cancer chemoprevention. 

The project will employ state-of-the-art molecular and cellular biology approaches, including ChIP-seq, RNA-seq, DNA methyl-seq and other large-scale epigenomic and chromatin analyses, including at the single-cell level; cell imaging; state-of-the-art gene manipulations using RNAi and CRISPR/Cas9 technology. In addition, we routinely employ sophisticated mouse models and human tissues.

The lab strives to be highly collaborative with other labs in San Diego, the US and elsewhere, for example collaborating with computational biologists, immunologists, experts in specific mouse models of cancer and aging, and surgeons, pathologists and clinical oncologists.

Requirements

Candidates should have, or be working towards, a PhD or equivalent degree in a biological science. Expertise in some aspect of cell and/or molecular biology and/or animal models is essential. The Adams lab has dedicated computational biology support for data analysis, so computational expertise is an advantage, but not essential. Successful applicants will have opportunity to learn computational approaches for analysis of large datasets, a big advantage in the competitive job market. 

Interested candidates should send an email with a summary of achievements and research interests, updated CV and contact information for 3 letters of reference to Dr. Peter Adams via the Apply button below.

Please visit https://chromatin.wordpress.com for additional information.

Apply Share
See details
Position
Tumor Initiation and Maintenance Program: Cancer Epigenetics - Deshpande Lab
Location
La Jolla
Research

A postdoctoral position is available with a flexible start date in the field of epigenetics in the Deshpande Lab at the Sanford Burnham Prebys Medical Discovery Institute (SBP) in La Jolla, California. SBP is known for its world-class capabilities in stem cell research and drug discovery technologies and is an NCI-designated Cancer Center. SBP is located on the scenic Torrey Pines Mesa and has collaborative ties to several adjacent world-class research institutions such as the Salk Institute, Scripps and the University of California San Diego as well as several leading pharmaceutical companies.

The Deshpande Lab is interested in cancer epigenetics with a core focus on hematological malignancies using mouse models. The lab also has a strong interest in normal hematopoietic stem cell biology. The candidate will be involved in the study of normal and cancerous stem cells using genomic, epigenomic and biochemical methods, high-throughput small molecule inhibitor screens and CRISPR-Cas9 mediated genome editing.

Requirements

Highly motivated candidates with a recent Ph.D. in Cell Biology, Molecular biology, Genetics or relevant fields are encouraged to apply. Experience and expertise in cell and molecular biology (multi-parameter flow cytometry, chromatin immunoprecipitation, cell culture) and/or mouse models of hematopoiesis is highly desired. Basic knowledge of computational data analysis is a big plus but not a must. We are seeking collaborative individuals who are detail oriented, with excellent communication and data organization skills. Candidates must have a demonstrated ability to successfully spearhead a research project as evidenced by first author publications in reputable and high impact journals (published or submitted).

Interested candidates should send an email with a summary of achievements and research interests, updated CV and contact information for three letters of reference to Dr. Ani Deshpande the Apply button below.

Apply Share
See details
Position
Faculty Opportunities in Cancer Immunology
Tracking #
cc1115
Location
La Jolla
Research

The NCI-designated Cancer Center at SBP seeks junior, mid-career, and senior faculty to lead cutting-edge research programs in Cancer Immunology and Immunotherapy. Areas of interest include: anti-tumor immunity, tumor-promoting inflammatory cells and their products, immune recognition of tumor-specific antigens, and understanding the immunomodulatory effects of current and prospective cancer treatments.  The SBP Cancer Center provides state-of-the-art laboratories and shared resources supported by a collaborative work environment.
 

Requirements

The Faculty positions require a Ph.D. or M.D./Ph.D. and an outstanding record of publications and research accomplishments relevant to the focus areas.  Chosen candidates are expected to establish well-supported, rigorous and competitive research programs based on fundamental mechanisms that can address unmet clinical needs. 

To apply for consideration:

Interested applicants should send their CV, together with a cover letter, a short summary of past accomplishments, an outline of future research plans and, for assistant professor candidates, the contact information for 3-4 references to facultyrecruiting@SBPdiscovery.org.  All application materials should be sent as a single PDF file with code #cc1115 referenced in the subject line. 

Apply Share
See details