The path to discovery

We apply our fundamental understanding of the biology and chemistry of disease to the development of revolutionary medical therapies.

Medical Discovery

Our path to discovery starts with our highly qualified and experienced scientists who work collaboratively to answer fundamental biological questions and better understand human health.


Translational Centers

Scientists work across five disease-focused translational centers to conduct their research.

• NCI-Designated Cancer Center

• Infectious and Inflammatory Disease Center

• Neuroscience and Aging Research Center

• Center for Metabolic Origins of Disease

• Sanford Children's Health Research Center


Within these translational centers, research groups focus on specific programs including:

• Tumor Initiation and Maintenance Program

• Cancer Metabolism and Signaling Networks Program

• Tumor Microenvironment and Cancer Immunology Program

• Degenerative Diseases Program

• Development, Aging and Regeneration Program

• Immunity and Pathogenesis Program

• Human Genetics Program

• Cardiovascular Metabolism Program

•  Integrative Metabolism Program

•  Genomic Control of Metabolism Program

•  Bioinformatics and Structural Biology Program