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Florida Translational Research Program

“There is no doubt we have the talent here in Florida to develop the medicines of tomorrow. Through the Florida Translational Research Program, we have the opportunity to match this talent with our infrastructure and technology platforms at Sanford Burnham Prebys.”

- Layton Harris Smith, Ph.D.
Director of Drug Discovery, Florida

We are pleased to announce that the FTRP was funded by the Florida legislature for FY 2016-2017. 

SBP thanks Governor Scott, the Senate and House of Representatives for supporting biomedical research and recognizing the power of the FTRP to translate discoveries statewide into breakthrough medicines. 
 

Proposals

Proposals are solicited twice a year, in the spring and fall. Active solicitations and program forms are available for download here. Click Apply to be redirected to the application submission site.

The Florida Translational Research Program (FTRP) funds the discovery of new drugs to fight disease and reduce future health care costs. Discoveries emerging from research labs statewide are enhanced at SBP’s drug discovery center to create a pipeline of potential new medicines to fight cancer, Alzheimer’s disease, diabetes and to generate IP revenue. This university affiliated program has 100% participation by Florida universities with biomedical programs.
 

The FTRP...

Translates

...breakthrough discoveries from universities & nonprofit institutes into first-in-class therapeutics for patients.


Leverages

...the state’s investment in SBP’s drug discovery platform – the most advanced in the state & nonprofit world.


Accelerates

...the growth of Florida’s life sciences industry and advances discoveries to a stage that will be attractive for commercial investment.


Is competitive

– proposals are evaluated through a third-party peer-review process using the NIH review model.

 

program participant mapProgram Description

The purpose of the Florida Translational Research Program (FTRP) is to produce a pipeline of potential new medicines based upon laboratory research discoveries. The Program provides Florida-based scientists with access to experienced professionals and state-of-the-art technological resources for drug discovery to facilitate an interdisciplinary, collaborative approach to establish a pipeline of potential new treatments for today’s most challenging and unmet medical needs. The Program is funded by the state of Florida through the Florida Department of Health and is administered and performed by the Sanford Burnham Prebys Medical Discovery Institute at Lake Nona.

Sucess to-date

• Five pendiŸng patents

• Attracted nearly $5 million in out-of-state funding

• Commitments from venture capital firms to commercialize discoveries

• Completed 64 projects in cancer, neurological, diabetes and infectious disease research

Fact Sheet

 

    Leadership

    Layton Smith, Ph.D., Director, FTRP

    Watch Dr. Layton Smith describe the program and discuss its successes.

    Dr. Kyle Rohde, UCF College of Medicine

    Watch Dr. Rhode discuss how the FTRP benefitted his research.

    Case Histories

    University of South Florida

    nash & USF logo
    Dr. Kevin Nash has identified a protein that can reduce inflammation in diseased brains and rescue neurons. The USF/SBP team sought to identify molecules that would mimic the anti-inflammatory protein. Equipped with strong data, Dr. Nash has applied for an Alzheimer’s Drug Discovery Foundation grant.

    Mayo Clinic Jacksonville

    McLean & mayo clinic logo
    Dr. Pamela McLean is searching for breakthrough Parkinson’s disease therapies. Her FTRP collaboration provided access to SBP’s 900,000 compound library and industry-trained drug discovery experts. Initial results led to a Michael J. Fox Foundation award—the largest MJFF grant ever awarded—demonstrating the ability of FTRP to enhance Florida research and attract out-of-state funding.

    Moffitt Cancer Center

    Sebti Lawrence & Moffitt logo
    Drs. Said Sebti and Nicholas Lawrence are leading the charge to identify potent small molecules that will suppress tumor growth. With FTRP support, the Moffitt/SBP team seeks to identify chemicals that will kill cancer cells and then advance the compounds to the clinic, where they hope to broaden the spectrum of tumors that can be successfully treated.

    Florida International University

    Tse-Dinh & FIU logo
    Dr. Yuk-Ching Tse-Dinh seeks to discover new antibiotics to combat multidrug-resistant infections. Working with Dr. Tse-Dinh, SBP drug discovery scientists searched for new chemicals that might kill antibiotic-resistant bacteria. The need is great since all antibiotics in use today were discovered more than 30 years ago. The FTRP funding put research back on course to address the worldwide crisis.

    University of Florida

    Conrad & UF logo
    Dr. Kirk Conrad studies relaxin, one of the body’s molecules that control blood pressure. His FTRP funded collaboration with SBP led the team to identify potential drug like molecules that mimic the effects of relaxin in test tubes, which in time may be the next best medicine for treating heart failure. This project has attracted the interest of a major pharmaceutical company.

    Q & A

    What is the status of the Florida Translational Research Program?

    We are pleased to announce that the FTRP was funded by the Florida legislature for FY 2016-2017.

    Sanford Burnham Prebys (SBP) thanks Governor Scott, the Senate and House of Representatives for supporting biomedical research and recognizing the power of the FTRP to translate discoveries statewide into breakthrough medicines. 
     

    May I pursue collaborative research with Sanford Burnham Prebys Medical Discovery Institute?

    Of course! The drug discovery team at SBP is hard at work seeking novel treatments for today’s most challenging and unmet medical needs. And we are available to collaborate on your research project. Please contact us for more information.
     

    Whom do I contact if I have any questions?

    You may reach a member of the FTRP team at ftrp@SBPdiscovery.org.

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    Program Participants
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