beakers drying on rack

Programs

Where Independent Minds Come Together

The Institute's research programs consist of a group of independent investigators working together to answer fundamental biological questions. This focused approach creates opportunities for collaboration among research labs and contributes to a scientifically stimulating environment.

protein interaction network
Bioinformatics and Structural Biology Program
Quantitative understanding of biological systems on the molecular level in normal and disease states to modify and control critical events to promote human health.
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intestinal epithelia
Cancer Metabolism and Signaling Networks Program
Cancer overruns cell programs, allowing tumors to take root.
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Cardiovascular Metabolism
Cardiovascular Metabolism Program
Investigating the body’s metabolism system is leading to novel targets and therapeutics aimed at cardiovascular disease.
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Differentiation of Neural Stem Cells
Degenerative Diseases Program
Understanding age-associated complex diseases will lead to progress in treatments for dementia, Alzheimer’s or Parkinson’s disease.
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developing human islets
Development, Aging and Regeneration Program
Our scientists are discovering how organs form and deteriorate with a goal to find ways to reverse or ameliorate aging and muscle wasting diseases.
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illustration of interior of cell nucleus
Genomic Control of Metabolism Program
Genetic blueprints teach us how genetic, genomic and epigenetic mechanisms control physiology and metabolism in health and disease.
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Human Genetics Program
Human Genetics Program
Technological breakthroughs are helping diagnose and explain known genetic diseases.
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lymph node with abscess; image from NIH Image Gallery
Immunity and Pathogenesis Program
Understanding the nature of inflammation and immunity helps scientists formulate new approaches to treat diseases like AIDS, influenza, autoimmunity, and cancer.
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Integrative Metabolism Program
Integrative Metabolism Program
Fundamental and translational research in metabolism can help solve obesity-related diabetes and its complications.
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fluorescently stained skin cancer sample
Tumor Initiation and Maintenance Program
Something goes wrong in a cell, sending it spinning out of control.
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fluorescently stained tumor sample
Tumor Microenvironment and Cancer Immunology Program
Tumors create a niche environment to spread. The immune system can be guided to fight cancer.
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