SBP News Archive

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Genetic drivers of immune response to cancer discovered through ‘big data’ analysis

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2016 15 Articles Back to Top
July 18th

Genetic drivers of immune response to cancer discovered through ‘big data’ analysis

Findings could lead to new immunotherapies

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July 14th

Dietary Restriction Increases Lifespan Through Effects on the Gut

Research shows that cell recycling in the intestine is important for healthy aging

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June 27th

Scientific Breakthrough May Limit Damage Caused by Heart Attacks

Research identifies master controller of blood vessel growth in the heart

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June 23rd

New Technology Could Deliver Drugs to Brain Injuries

Peptide carries molecules and nanoparticles to acutely damaged areas of the brain

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June 13rd

SBP Scientist Selected to Conduct Novel Medical Research in Space

Disease modeling experiment will be her second project on the ISS

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June 8th

Sanford Burnham Prebys Selected as Designated Center for Chemical Biology Consortium

SBP will be awarded Master Service Agreements with funding for drug discovery

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May 25th

Study Reveals Protein That Dials Immune Responses Up and Down

Researchers establish PSGL-1 as regulator of immune checkpoints

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May 18th

High Levels of Protein p62 Predict Liver Cancer Recurrence

Study in mice and human tissues suggest new prognostic and therapeutic approach

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May 17th

Researchers Identify Super-Oncogenic Protein That Promotes Development of Melanoma

Findings may help identify especially aggressive tumors

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April 19th

SBP and GSK Create New Center for Translational Neuroscience

Academic-industry alliance seeks to find and validate new targets for drug development

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February 16th

Renowned Biochemist, Marcia I. Dawson, Has Died

Marcia I. Dawson, whose pioneering research helped lay the groundwork for pro-apoptotic (programmed cell death) small molecules for the treatment of cancer, died recently at her home in Menlo Park, California.

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February 10th

Researchers Resolve Longstanding Issue of Components Needed to Regenerate Muscle

Findings clear path to devise new treatments for muscular injuries and dystrophies

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February 2nd

SBP Investigator Receives Outstanding Investigator Grant Through New National Cancer Institute Program

Seven-year award will support Ze’ev Ronai’s research on tumor adaptations to survive harsh conditions

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January 26th

Failing Hearts Switch Fuels to Generate Energy

Findings suggest a new approach to treat early heart failure.

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January 19th

Researchers Reveal Structure of Protein Complex That Plays Key Role in Modulating Immune System

Search for new inflammatory disease drugs may be aided by detailed structure of distinct ubiquitin ligase complex.

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2015 24 Articles Back to Top
December 14th

New Vice President of Strategic Alliances at SBP

Letizia Amadini-Lane takes key position at SBP

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December 8th

Using “Big Data” to Combat Influenza

Team of scientists from the Icahn School of Medicine at Mount Sinai and Sanford Burnham Prebys Medical Discovery Institute among those who combined large genomic and proteomic datasets to identify novel host targets to treat flu

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December 3rd

A Dietary Sugar That May Prevent Melanoma From Metastasizing

Dietary fucose supplementation found to suppress the growth of melanoma

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November 24th

Scientists Identify Promising New Melanoma Drug

The first-in-class compound halts tumor growth by disrupting protein production

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October 19th

How Proteins Age

SBP researchers and colleagues discover a mechanism that regulates the aging and abundance of secreted proteins.

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October 19th

‘Big Data’ Used to Identify New Cancer Driver Genes

SBP researchers combine publicly available cancer databases to identify new genes associated with cancer.

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September 8th

Researchers Reawaken Sleeping HIV in Patient Cells to Eliminate the Virus

An emerging class of drugs called Smac mimetics may lead to a safe and effective treatment to eradicate HIV.

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August 31st

New Insights on How Protein Tangles Accumulate in the Brain and Cause Neurological Disorders

The appoptosin protein initiates a path that leads to the accumulation of tau, a key component of brain lesions.

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August 13rd

Scientists Discover a Pathway That Controls Cancer Cell Proliferation by Nutrients

The findings introduce new drug targets to selectively inhibit a key event in tumor cell progression

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July 30th

Sanford Burnham Prebys Medical Discovery Institute’s Graduate School of Biomedical Sciences Receives WASC Accreditation

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July 24th

Researchers find new method to halt the advance of liver cancer

Study suggests that drugs targeting the lymphotoxin-beta receptor may improve liver cancer treatment

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July 20th

Sanford Burnham Prebys Medical Discovery Institute Spin-Out Company micro-gRx Receives $200,000 Space Florida Award

The company and its partners are developing a “lab on a chip” research model to enable human-cell analysis in microgravity.

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June 24th

Conrad Prebys donates $100 million to Sanford-Burnham

The Institute will be renamed to honor his exceptional generosity and use the gift to accelerate the discovery of innovative therapeutics

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June 4th

Research Offers a New Approach to Improving HIV Vaccines

Researchers identify a molecule that recognizes HIV and initiates an immune response. The findings could help improve the efficacy of HIV vaccines to prevent infection.

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May 28th

Sanford-Burnham partners with Takeda on novel treatment for cardiovascular disease

Teams of scientists at the two organizations collaborate to identify molecules that reactivate dormant proteins in heart failure

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May 28th

Sanford-Burnham Researchers Identify a New Target for Treating Drug-Resistant Melanoma

Study explains why some melanoma tumors are resistant to BRAF inhibitor treatment

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May 14th

Lilly and Sanford-Burnham Announce Collaboration to Investigate Immunological Therapies

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April 23rd

Sanford-Burnham Welcomes Stuart Tanz and Carol Gallagher to Its Board of Trustees

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April 20th

Pancreatic cancer breakthrough: Scientists turn cancer cells into normal cells

Scientists find a novel avenue for therapeutic intervention of the 'silent cancer'

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April 2nd

Sanford-Burnham licenses small molecule to Daiichi Sankyo for further development

Scientists at the Institute developed a small molecule to prevent cardiovascular-metabolic disease; The collaboration strives to accelerate the discovery to affected patients

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March 9th

Study Explains Control of Cell Metabolism in Patient Response to Breast Cancer Drugs

Researchers identify a control mechanism for glutamine uptake in breast cancer cells and its importance for response to select chemotherapies.

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February 27th

Michael Ayers Joins Sanford-Burnham at Lake Nona as Associate Director of Government Relations

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February 5th

New study sheds light on cancer stem cell regulation

Researchers identify signaling molecules in intestinal stem cells that can lead to tumors if left unregulated. The findings suggest a new approach to targeting intestinal cancers.

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January 27th

Using stem cells to grow new hair

Researchers develop method to induce human hair growth using pluripotent stem cells

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2014 26 Articles Back to Top
December 16th

National Academy of Inventors Names Two Sanford-Burnham Researchers as Charter Fellows

Erkki Ruoslahti and Kristiina Vuori have been named NAI Fellows—a professional distinction accorded to academic inventors who have demonstrated a prolific spirit of innovation.

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December 1st

Sanford-Burnham Scientist Wins GlaxoSmithKline Drug Discovery Challenge to Develop New Therapy for High Blood Pressure

A team of Sanford-Burnham and Mayo Clinic researchers will work with GlaxoSmithKline to develop a novel treatment for resistant high blood pressure.

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November 3rd

Tanz Family Gives $1 Million to Sanford-Burnham and the University of Toronto to Fund Neurodegenerative Research

The philanthropic gift establishes a joint effort between Sanford-Burnham and the Tanz Centre at the University of Toronto to find new therapeutic treatments for neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, and ALS.

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October 29th

Sanford-Burnham Recruits Leading Cardiometabolic Experts to Its Medical City Campus in Lake Nona

The arrival of two cardiometabolic researchers in Orlando brings cutting-edge health care now and in the future.

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October 23rd

New insight on why people with Down syndrome invariably develop Alzheimer's disease

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October 9th

Researchers Find RNA Molecules in Urine and Tissue That Detect Prostate Cancer

Potential Biomarkers May Pave Way to a More Sensitive, Specific, and Non-Invasive Prostate Cancer Screening Assay, According to Report in The Journal of Molecular Diagnostics

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September 18th

Sanford-Burnham Medical Research Institute Welcomes Five New Trustees

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September 7th

Researchers discover a key to making new muscles

A new study finds that cyclic bursts of a STAT3 inhibitor can replenish muscle stem cells and promote their differentiation into muscle fibers. The findings are an important step toward developing and maintaining new muscle to treat muscle diseases

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August 19th

Sanford-Burnham Appoints Perry Nisen as Chief Executive Officer

Dr. Nisen will lead the implementation of Sanford-Burnham’s new 10-year strategic vision and expand the Institute’s therapeutics discovery efforts.

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July 31st

A new way to generate insulin-producing cells in Type 1 diabetes

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July 17th

Researchers discover new link between obesity, inflammation, and insulin resistance

Study finds that the NBR1 protein plays a critical role in regulating obesity-induced inflammation that leads to metabolic disease

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July 3rd

A 'switch' in Alzheimer's and stroke patient brains that prevents the generation and survival of neurons

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July 3rd

New study reveals how tumors remodel their surroundings to grow

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June 25th

Sanford-Burnham acquires revolutionary equipment to advance HIV research

Funding from the James T. Pendleton Trust secures new instrument that enables simultaneous detection and characterization of blood cells targeted by HIV.

The instrument, an Amnis® ImageStreamX Mark II, enables researchers to obtain high resolution images to visualize rare events that occur between and within individual cells.

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June 22nd

Researchers discover new genes that promote brain cancer

Study identifies 2 novel oncogenes that cause childhood brain cancer when activated

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May 21st

Sanford-Burnham and Daiichi Sankyo form alliance to study novel drug targets

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May 12nd

Researchers find new molecule to treat asthma

Study identifies a novel molecule that prevents the symptoms associated with allergen-induced asthma

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April 30th

Researchers Reveal New Cause of Epilepsy

Study shows the first evidence that hyaluronic acid plays a role in epileptic seizures, providing a potential new approach for treatments.

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April 18th

Proteins Conspire to Make Breast Cancer Cells Resistant to Drug Treatment

Sanford-Burnham researchers discover that the interaction between two proteins called BCAR1 and BCAR3 is responsible for resistance to antiestrogen drugs, paving the way for improved diagnostic and treatment strategies.

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April 11st

Regenerating muscle in Duchenne muscular dystrophy: Age matters

Researchers reveal novel cellular and molecular elements of muscle repair. The study explains how drugs can induce regeneration, while preventing fibrosis and fat deposition, in dystrophic muscle at early stages of Duchenne muscular dystrophy

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April 3rd

Sanford-Burnham presents cancer research at AACR

Sanford-Burnham cancer research highlights will be presented at the 105th Annual Meeting of the American Association for Cancer Research held April 5-9, 2014, in San Diego

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March 25th

Replacing insulin through stem cell-derived pancreatic cells under the skin

A newly created method of placing stem cell-derived pancreatic cells in capsules under the skin to replace insulin is tested in diabetic disease models

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March 25th

Unravelling nerve-cell death in rare children's disease

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March 12nd

Carol Cox Joins Sanford-Burnham as Senior Vice President of External Relations

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March 12nd

Key heart-failure culprit discovered

Collaborative research study by Sanford-Burnham, Icahn School of Medicine at Mount Sinai, and UC San Diego shows blocking microRNA miR-25 halts progression of heart failure, improves cardiac function, and may increase survival

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January 28th

Sanford-Burnham Board of Trustees Approves New 10-Year Strategic Vision

Landmark Gift Will Launch Implementation

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2013 32 Articles Back to Top
November 27th

Genetic mutation increases risk of Parkinson’s disease from pesticides

Study uses patient-derived stem cells to show that a mutation in the α-synuclein gene causes increased vulnerability to pesticides, leading to Parkinson’s disease.

LA JOLLA, Calif., and CAMBRIDGE, Mass., November 27, 2013 – A team of researchers has brought new clarity to the picture of how gene-environmental interactions can kill nerve cells that make dopamine. Dopamine is the neurotransmitter that sends messages to the part of the brain that controls movement and coordination. Their discoveries, described in a paper published online in Cell today, include identification of a molecule that protects neurons from pesticide damage.

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November 12nd

Sanford-Burnham receives US Air Force grant to perform next-generation toxicity screens

The 3-year project assesses the health risk of exposure to chemicals by utilizing Sanford-Burnham's state-of-the-art chemical-screening platform and stem-cell expertise

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October 1st

Sanford-Burnham’s Kristiina Vuori Appointed to Florida Inventors Hall of Fame Advisory Board

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September 25th

New approach to treating human brain cancer could lead to improved outcomes

Disrupting cancer stem cells in medulloblastoma blocks cell division, induces cell death, and overcomes tumors resistant to therapy. Targeting the cell-division cycle may lead to improved outcomes for patients with this highly malignant cancer

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September 20th

Kristiina Vuori Joins California Breast Cancer Research Council

Sanford-Burnham president and interim CEO will help oversee nation’s largest state-funded cancer-research effort.

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September 16th

Sanford-Burnham researchers identify new target for melanoma treatment

The PDK1 gene, known to regulate many cell functions such as metabolism and survival, is now identified as a key regulator in melanoma development and metastasis, offering opportunities to interfere with cancer progression

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August 13rd

Sanford-Burnham collaborates with Pfizer to identify targets for insulin resistance and diabetes

Collaboration utilizes Sanford-Burnham drug discovery platform to find new therapeutic targets for treating complications of obesity and diabetes

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August 8th

Sanford-Burnham scientists identify key protein that modulates organismal aging

The findings could lead to the development of therapeutic agents for age-related diseases

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August 4th

Sanford-Burnham Saddened by Loss of Biotechnology Leader Duane Roth

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August 1st

Sanford-Burnham researchers map a new metabolic pathway involved in cell growth

A more complete understanding of the pathway could lead to new treatments for disease

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July 30th

Sanford-Burnham researchers uncover how a potent compound kills prostate cancer cells

SMIP004 holds promise as a novel, much-needed treatment for advanced prostate cancer

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July 9th

Sanford-Burnham researchers develop novel nanoparticle to deliver powerful RNA interference drugs

The approach points the way toward new ways to silence malfunctioning genes

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June 17th

Sanford-Burnham researchers develop new drug that reverses loss of brain connections in Alzheimer's

NitroMemantine is the first drug to halt the progression of synaptic loss and to even restore these connections between nerve cells. The combination drug is now headed for clinical trials

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June 10th

Shape of nanoparticles points the way toward more targeted drugs

A collaboration of scientists at Sanford-Burnham and the University of California, Santa Barbara, finds that rod-shaped particles, rather than spherical particles, appear more effective at adhering to cells

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May 16th

Sanford-Burnham researchers identify target to prevent hardening of arteries

The gene Dkk1 encodes a protein that plays a key role in increasing the population of connective-tissue cells during wound repair, but prolonged Dkk1 signaling can lead to fibrosis and a stiffening of artery walls

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May 14th

Sanford-Burnham Recruits Genomics Expert László Nagy, M.D., Ph.D., to Head New Multidisciplinary Research Program

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May 10th

A cautionary tale on genome-sequencing diagnostics for rare diseases

Sanford-Burnham researchers discover that several children born with rare diseases called congenital disorders of glycosylation don't contain the mutation in every cell type -- raising new questions about inheritance, genomic sequencing, and diagnostic

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May 8th

Differences between 'marathon mice' and 'couch potato mice' reveal key to muscle fitness

MicroRNAs are identified as the missing link between the 2 defining features of muscle fitness -- fuel-burning and fiber-type switching -- providing a potential new target for interventions that boost fitness in people with chronic illness or injury

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April 2nd

White blood cell enzyme contributes to inflammation and obesity

An imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver in mice and humans -- providing a new therapeutic target for these health conditions

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April 1st

Newly identified tumor suppressor provides therapeutic target for prostate cancer

Sanford-Burnham researchers discover that, in both mice and humans, the enzyme PKCzeta acts as a tumor suppressor by keeping the pro-tumor c-Myc gene in check

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March 24th

Sanford-Burnham researchers unravel molecular roots of Down syndrome

Sanford-Burnham researchers discover that the extra chromosome inherited in Down syndrome impairs learning and memory because it leads to low levels of SNX27 protein in the brain

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March 18th

How some prostate tumors resist treatment - and how it might be fixed

Sanford-Burnham researchers discover that a protein called Siah2 helps prostate cancer cells resist hormone therapy - making it an attractive biomarker and therapeutic target

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March 13rd

Molecule's structure reveals new therapeutic opportunities for rare diabetes

3-D structure of HNF-4alpha, a protein mutated in a rare, inherited form of diabetes, reveals new pockets that could be targeted with therapeutic drugs

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March 11st

Sanford-Burnham Medical Research Institute and Mayo Clinic extend collaborative agreement

Researchers at the 2 organizations will work together to identify and validate compounds -- prototype drugs -- that show promise against clinically relevant targets

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March 4th

Sanford-Burnham and 60° Pharmaceuticals to pursue promising target for the treatment of dengue fever

New partnership investigates potential inhibitors of furin, a protein vital to the lifecycle of dengue fever virus and other infectious tropical diseases.

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February 11st

Sanford-Burnham and Florida Hospital renew research partnership with Takeda

Novel model for collaboration combines basic and clinical research with drug development to find new obesity therapeutics

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February 4th

Chemical reaction keeps stroke-damaged brain from repairing itself

In stroke and other neurological disorders, nitric oxide damages neurons and blocks the brain's ability to repair itself

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January 31st

How cancer cells rewire their metabolism to survive

Sanford-Burnham researchers discover that tumors lacking the protein PKCz are good at surviving when nutrients are scarce—opening a new therapeutic avenue that targets cancer metabolism

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January 27th

Patients' own skin cells are transformed into heart cells to create 'disease in a dish'

Researchers use skin cells from patients with an inherited heart condition to recreate the adult-onset disease in a laboratory dish -- producing the first maturation-based disease model for testing new therapies

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January 15th

Diabetic fruit flies support buzz about dietary sugar dangers

First fruit fly model of diet-induced type 2 diabetes shows how high-sugar diet affects the heart and reveals new therapeutic opportunities

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January 4th

Shifting the balance between good fat and bad fat

Sanford-Burnham researchers show that protein p62 balances metabolism in fat tissue-making it an attractive target for anti-obesity therapies

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January 3rd

Sanford-Burnham and Intrexon Corporation establish collaboration to accelerate stem cell research

Combines Sanford-Burnham Medical Research Institute's renowned scientific team and Intrexon's proprietary discovery platforms to accelerate human induced pluripotent stem cell research

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2012 39 Articles Back to Top
December 19th

Transplanted neural stem cells treat ALS in mouse model

In 11 independent studies, a consortium of ALS researchers shows that transplanting neural stem cells into the spinal cord of an ALS mouse model slows disease onset and progression, improves motor function, and significantly prolongs survival

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December 3rd

'Junk DNA' drives embryonic development

Sanford-Burnham researchers discover that microRNAs play an important role in germ layer formation—the process that determines which cells become which organs during embryonic development

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November 29th

Sanford-Burnham research projects selected to go to space

Space Florida to send two experiments from Sanford-Burnham Medical Research Institute to the International Space Station

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November 27th

Compound found in rosemary protects against macular degeneration in laboratory model

Sanford-Burnham researchers discover that carnosic acid, a component of the herb rosemary, promotes eye health in rodents—providing a possible new approach for treating conditions such as age-related macular degeneration

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November 15th

Neurons made from stem cells drive brain activity after transplantation in laboratory model

Sanford-Burnham researchers convince transplanted stem cell-derived neurons to direct cognitive function -- getting us a step closer to using these cells to treat Alzheimer’s disease and other neurodegenerative conditions

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November 13rd

For brain tumors, origins matter

Sanford-Burnham researchers discover that brain tumors arising from different cell types might require different—and more personalized—treatment approaches

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November 9th

Hunting neuron killers in Alzheimer's and TBI

Sanford-Burnham researchers discovered that the protein appoptosin prompts neurons to commit suicide in several neurological conditions—giving them a new therapeutic target for Alzheimer's disease and traumatic brain injury

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September 25th

Making it easier to make stem cells

Sanford-Burnham researchers identified kinase inhibitors that lower the barrier to producing stem cells in the laboratory—cells important for disease research and drug development

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September 20th

Sanford-Burnham's Erkki Ruoslahti named to Thomson Reuters' Nobel Prize watch list

Erkki Ruoslahti, M.D., Ph.D., cancer researcher and distinguished professor at Sanford-Burnham Medical Research Institute, has been named a 2012 Thomson Reuters Citation Laureate, placing him on the organization's list of 'Nobel class' scientists

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September 13rd

NIH New Innovator Award helps Sanford-Burnham scientist pursue high-risk, high-reward project

With this award, Duc Dong, Ph.D. will explore genetic reprogramming as a means to grow replacement organs in an adult animal model

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September 12nd

California's stem cell agency boosts heart disease research at Sanford-Burnham

Huei-Sheng Vincent Chen, Ph.D. receives $1.58 million CIRM Basic Biology IV award to develop personalized models of inherited heart conditions using stem cells derived from patients' own skin cells

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August 20th

Brain enzyme is double whammy for Alzheimer's disease

Sanford-Burnham researchers discover that an enzyme known for generating toxic brain plaques in Alzheimer's disease also causes additional memory and cognitive deficits via a separate mechanism

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August 13rd

Protein that helps tumor blood vessels mature could make cancer drugs more effective

Sanford-Burnham researchers discover molecule that controls tumor vessel maturation—a counterintuitive approach that could improve cancer drug delivery

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August 2nd

Mending a broken heart—with a molecule that turns stem cells into heart cells

Researchers discovered a molecule that converts stem cells into heart cells, which could be used to replace diseased or damaged tissue in heart disease patients

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July 18th

Discovery of new heart failure trigger could change the way cardiovascular drugs are made

Researchers find that the switch between healthy and failing heart depends on the way one particular heart protein is activated -- important news for drug makers targeting the protein to treat cardiovascular disease

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May 9th

It's a trap! New laboratory technique captures microRNA targets

Sanford-Burnham researchers develop a method called miR-TRAP, which allows scientists to better understand the roles microRNAs play in human development and disease,

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May 3rd

TGen leads new National Institutes of Health study of brain tumors

Sanford-Burnham Medical Research Institute, Van Andel Research Institute and Thomson Reuters participate in search for new drugs to treat glioblastoma multiforme

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March 27th

Translational Research Institute Seeks Individualized Approaches to Curing Global Epidemic of Diabetes

Innovative partnership between Florida Hospital and Sanford-Burnham Medical Research Institute will bridge research and treatment to accelerate personalized medicine in diabetes and obesity

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March 27th

National High Five Day will benefit cancer research at Sanford-Burnham Medical Research Institute

Sanford-Burnham Medical Research Institute (Sanford-Burnham) is one of four beneficiaries of this year’s National High Five Day and its program, the High-Five-a-Thon for Cancer Research, taking place on April 19.

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March 19th

Sanford-Burnham scientists unravel cancer drug's secret to resistance

Study outlines new method to test a tumor's resistance to an experimental therapy and pinpoint the genetic culprit before testing the drug in patients—providing a new path toward personalized medicine

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March 18th

New insight into mechanisms behind autoimmune diseases suggests a potential therapy

Sanford-Burnham study shows how the breakup of 2 proteins interferes with the immune system and demonstrates that inhibiting 1 of the errant proteins restores proper function

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March 14th

Genome-wide study reveals how key immune sensors arrive at the front lines of infection

Researchers identify 190 genes crucial to the function of TLR7 and TLR9, cellular sensors that recognize pathogens and trigger immune responses -- providing insights that could be exploited to develop new therapies for infectious and autoimmune diseases

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March 12nd

Research on rare bone disorder reveals new insights into autism

Sanford-Burnham researchers discover the molecular basis of autistic symptoms in children with a rare bone disorder -- findings that also provide new insights for the general autistic population

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March 6th

Sanford-Burnham Obesity Research Advances to Patient Studies at Florida Hospital – Sanford-Burnham Translational Research Institute

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February 28th

Sanford-Burnham Challenges Supporters to “Get Real” for Stem Cell Research

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February 24th

Sanford-Burnham Medical Research Institute intern Erin Singer makes art out of science

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February 23rd

Disarming the botulinum neurotoxin

Sanford-Burnham researchers determine the first 3-D structure of the botulinum neurotoxin, together with the protein bodyguard that guides it through the body -- revealing weak spots that could be exploited to develop new counterterrorism measures

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February 22nd

University of Florida President Appointed to Sanford-Burnham’s Board of Trustees

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February 16th

Scripps Research and Sanford-Burnham scientists shed light on how body fends off bacteria

Team develops first 3D look at interaction between immune sensor and protein that helps bacteria move

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February 15th

Sanford-Burnham Medical Research Institute and Florida Hospital Review Obesity Research Progress with Collaborator Takeda Pharmaceutical

The mid-term report lays groundwork for next phase of study

The two-year collaboration focuses on the discovery and evaluation of new therapeutic approaches to obesity.

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February 13rd

New model of childhood brain cancer establishes first step to personalized treatment

Sanford-Burnham researchers create a new mouse model for a particularly malignant form of medulloblastoma, and zero in on a potential therapy

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February 8th

Moffitt, Sanford-Burnham and Florida Hospital create Personalized Medicine Partnership of Florida

Partnership will conduct collaborative research to accelerate discovery and develop new treatments in the areas of cancer and metabolic diseases, including obesity, diabetes, and cardiovascular disease

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February 6th

Heart hormone helps shape fat metabolism

Sanford-Burnham study shows that the pathway to losing fat is heavily influenced by a hormone produced in the heart

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February 6th

Tasting fructose with the pancreas

Sanford-Burnham researchers discover taste receptors in pancreatic beta cells that can sense fructose and stimulate insulin secretion

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February 2nd

Sanford-Burnham researchers find molecular switch that allows melanoma to resist therapy

Study identifies protein kinase Cε as a molecular switch that determines tumor-promoting or -suppressing activity in skin cells

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February 1st

Sanford-Burnham’s Center for Nanomedicine receives grant from Hearst Foundations

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February 1st

How antipsychotic medications cause metabolic side effects such as obesity and diabetes

Sanford-Burnham study suggests that many antipsychotics affect metabolism because they activate the TGFβ pathway—a finding that could lead to safer therapeutics for bipolar disorder and schizophrenia patients.

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January 31st

Philanthropists Jeanne and Gary Herberger Endow Cancer Center Director Chair at Sanford-Burnham Medical Research Institute

The endowed chair adds to the generous support provided to Sanford-Burnham by the Herbergers in the past several years.

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January 4th

All weight gain is not the same

Study reveals overconsumption of calories increases fat storage, while higher percentage of protein builds lean body mass

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2011 31 Articles Back to Top
December 23rd

AAAS and Sanford-Burnham Announce 2011 Fellows

Dr. John Reed and Dr. Stuart Lipton elected by their peers

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December 15th

Sanford-Burnham scientist receives research grant from Novo Nordisk

Layton Smith, Ph.D., assistant professor and director of drug discovery, has been awarded a Novo Nordisk Diabetes Innovation Award, valued at $477,500 over two years.

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December 13rd

Two San Diego research groups named to Stand Up To Cancer Dream Team

Team to pioneer personalized medicine approach to treating melanoma

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November 30th

Super athletic mice are fit because their muscles burn more sugar

Mouse model shows that generating energy from sugar leads to fitter muscles and increased athletic ability

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November 21st

Researchers shrink tumors and minimize side effects using tumor-homing peptide to deliver treatment

Sanford-Burnham scientists show that coupling a tumor-homing peptide and an anti-cancer drug drastically reduces tumors in a mouse model of colon cancer, with no apparent side effects; technique could be applied to many types of cancer.

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November 17th

Mitochondria Restructuring Provides New Therapeutic Target for Heart Disease

Reducing a protein called Siah2 in mice improves mitochondrial response to low oxygen, a condition cells experience when blood flow is restricted during a heart attack.

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November 3rd

Sanford-Burnham Medical Research Institute and Pfizer Collaborate to Speed Drug Discovery

Sanford-Burnham Medical Research Institute (Sanford-Burnham) is the latest research organization to partner with Pfizer, Inc. as part of Pfizer’s commitment to transforming research and development through a focus on translational medicine.

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October 24th

First UCF/Sanford-Burnham Partnerships Produce Promising Cancer Research Results

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October 6th

How Cells Sense Nutrients and Fuel Cancer Cell Growth

Sanford-Burnham scientists identify a crucial new component of the machinery cells use to sense dietary amino acids—a mechanism that malfunctions in cancer

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October 4th

A Hormone that Fights Fat with Fat

Sanford-Burnham scientists reveal that a hormone called orexin prevents obesity in mice by activating brown fat, a tissue that’s good at burning calories.

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October 3rd

Nanoparticles Seek andn Destroy Glioblastoma in Mice

Sanford-Burnham and Salk Institute scientists combine tumor-targeting peptides and nanoparticles to eliminate glioblastoma in a previously untreatable mouse model

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September 19th

Sanford-Burnham Medical Research Institute Endorses California Cancer Research Act

Board of Trustees votes unanimously to support $1 increase in state tobacco tax to fund biomedical research in California

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September 13rd

Scripps Health and Sanford-Burnham Medical Research Institute to Collaborate to Advance New Cancer Treatments

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September 12nd

Oncothyreon Obtains Anti-Bcl-2 Compound from Sanford-Burnham Medical Research Institute; License Will Expand Oncology Product Development Pipeline

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September 6th

Recycling Fat Might Help Worms Live Longer

Sanford-Burnham researchers unravel how the interplay between two cellular processes—autophagy and lipid metabolism—influences lifespan in C. elegans worms.

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September 6th

Glucose Uptake Relies on Newly Identified Protein

Study reveals that insulin-stimulated glucose uptake—a process that breaks down in type 2 diabetes—requires a previously unidentified protein called CDP138

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August 15th

Study Finds Enzyme Disrupting Nerve Cell Communication in Alzheimer's Disease

A modified form of the enzyme Cdk5 is elevated in the brains of Alzheimer’s disease patients, where it triggers damage to nerve cell connections

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August 14th

How Fat and Obesity Cause Diabetes

High levels of fat shut down a key enzyme that promotes glucose sensing in pancreatic beta cells—revealing a pathway implicated in the type 2 diabetes epidemic

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July 25th

High-Throughput Screen Finds Compounds that Regulate Cancer Cell Invasion

Study uncovers several compounds that inhibit cancer cell invasion, but also reveals that cancer drug paclitaxel does the opposite—it promotes cancer metastasis

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July 12nd

Biochemist Randal J. Kaufman, Ph.D., Joins Sanford-Burnham Faculty

 

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May 10th

RNA Spurs Melanoma Development

 

Long non-coding RNA promotes melanoma cell survival and invasion – providing a potential new diagnostic marker for skin cancer

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May 5th

What Decides Neural Stem Cell Fate?

A gene called SOX2 acts as a stem cell gatekeeper – only cells expressing it have the potential to become neurons

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April 6th

Cellular Feast or Famine

Study shows how cells decide whether they have enough fat – a molecular checkpoint that, when disturbed, could lead to obesity or other diseases

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April 4th

Florida Hospital and Sanford-Burnham Welcome Diabetes and Obesity Expert Dr. Richard E. Pratley

Dr. Pratley will serve as Medical Director of Florida Hospital Diabetes Institute, Senior Faculty at the Translational Research Institute and Professor at Sanford-Burnham

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March 7th

A New Stem Cell Enters the Mix: Induced Conditional Self-Renewing Progenitor (ICSP) Cells

 

Generated from progenitor cells, ICSP cells are easier to produce than iPS cells and show therapeutic benefit in a rodent stroke model

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March 1st

How Long Do Stem Cells Live?

Unique computer model calculates how long a blood stem cell will live, information that could predict the outcome of bone marrow transplants

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February 1st

MicroRNA Cocktail Helps Turn Skin Cells into Stem Cells

New technique removes several hurdles in generating induced pluripotent stem (iPS) cells, smoothing the way for disease research and drug development

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January 25th

Remembering William H. Fishman, President Emeritus and Founder of The Burnham Institute, 1914-2001

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January 18th

A Different Path to Fat-Related Heart Disease

Fruit fly study demonstrates how lipotoxic cardiomyopathy might occur in genetically obese individuals, revealing potential therapeutic targets for fat-related heart disease

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January 17th

Sanford-Burnham Medical Research Institute Announces Collaboration with Ortho-McNeil-Janssen Pharmaceuticals, Inc.

Partnership to discover new medicines for Alzheimer's Disease and neuropsychiatric disorders

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January 6th

Sanford-Burnham Medical Research Institute Announces New Government Relations and External Relations Appointments

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2010 38 Articles Back to Top
December 27th

Florida Hospital, Sanford-Burnham Medical Research Institute and Takeda Announce Partnership to Target Obesity

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December 23rd

Protein Involved in Early Steps of Melanoma Development Revealed

Protein required for early stages of melanoma development can also predict melanoma outcome

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November 30th

The Couch Potato Effect

Deletion of key muscle protein inhibits exercise

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November 16th

Arthur Brody Pledges $1 Million to Sanford-Burnham

The gift will create the Art Brody Innovation Fund, which will support efforts to translate basic research discoveries into new medicines

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November 2nd

Fly Study Uncovers Molecular Link Between Obesity and Heart Disease

Researchers show that obesity-induced heart disease can be prevented by reducing the activity of TOR, a nutrient-sensing protein that regulates molecular circuits involved in growth, metabolism and lifespan

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November 1st

Study Finds Fat Hormone’s Long-Sought Link to Heart Protection

A protein called T-cadherin docks the fat hormone adiponectin to the heart, where it guards against stress-induced damage

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October 22nd

Breast Cancer Research Grants Awarded to Young Investigators at Sanford-Burnham Medical Research Institute at Lake Nona

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October 18th

SHIP Protein Identified as a B Cell Tumor Suppressor

Sanford-Burnham researchers discover how the enzyme SHIP regulates B cell growth in mice, findings that could impact lymphoma drugs in development

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October 8th

Manipulating Muscle Stem Cells to Treat Muscular Dystrophy

Scientists unravel the molecular link between damage-induced inflammation and muscle regeneration

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October 4th

Sanford-Burnham Pairs with MEDIT SA to Design Smarter Drugs

Powerful new software matches aberrant proteins with compounds that could fix them

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September 28th

Major Grant Renewal Boosts Sanford-Burnham Cancer Research

NCI core grant includes a 21 percent funding increase

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September 22nd

Lillian Fishman Honored by University of Alberta

Sanford-Burnham co-founder receives Distinguished Alumni Award

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September 8th

Sanford-Burnham Medical Research Institute Appoints New Business Development Executive

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September 7th

Carl Ware is Appointed Director of Sanford-Burnham’s Infectious and Inflammatory Disease Center

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August 18th

Study Explains Why Alzheimer’s Drug is Both Safe and Effective

Sanford-Burnham scientists uncover new clues to the molecular action of memantine, a drug used to treat Alzheimer’s disease, that show why side effects are rare

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August 4th

Cancer Researcher Wechsler-Reya Joins Sanford-Burnham Faculty

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July 29th

New Pathway to Parkinson’s and Alzheimer’s Diseases

Sanford-Burnham researchers uncover new clues about the cause of brain cell death in neurodegenerative disorders such as Parkinson’s, Alzheimer’s, and Huntington’s diseases

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July 14th

New Role for the JNK Protein

Researchers reveal that JNK, a protein long known to help cells respond to stress, also controls cell cycle

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July 12nd

Sanford-Burnham Medical Research Institute at Lake Nona Surpasses Mid-point for Faculty Recruitment

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July 12nd

How Prostate Cancer Packs a Punch

Researchers uncover a mechanism that determines prostate cancer aggressiveness, providing new targets for diagnosis and treatment

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June 29th

Sanford-Burnham Researchers Recognized by the NIH

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June 15th

Turning a Painkiller into a Cancer Killer

Sanford-Burnham researchers redirect a known pain reliever to trigger death pathways in cancer cells

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May 31st

New Answers on Rare Childhood Disease

New model reveals the molecular basis of multiple hereditary exostoses and provides a tool to screen new treatments

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May 11st

Cancer: Trapping the Escape Artist

Researchers deliver a better understanding of anti-cell death proteins and a potential antagonist to defeat them

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May 11st

Researchers Share Insights into RNA

32nd Annual Sanford-Burnham Scientific Symposium provides wealth of information on microRNAs and RNAi

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May 5th

Sanford-Burnham Researchers Awarded Two National Institutes of Health Grants

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April 16th

Sanford-Burnham Medical Research Institute at Lake Nona Boosts its Biomedical Research with the Appointment of Dr. Sheila Collins

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April 13rd

Dr. Kristiina Vuori Promoted to President of Sanford-Burnham Medical Research Institute

Pauline Foster Makes Gift to Endow Presidential Chair

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April 8th

Cancer Drug Effectiveness Substantially Advanced

Co-administered peptide directs medicines to tumors and deep into tumor tissue, increasing drug efficacy and reducing side effects

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April 1st

Mapping Heart Disease

Researchers uncover genes that may dramatically affect heart health

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March 12nd

Sanford-Burnham Medical Research Institute and Analiza, Inc. Add Large Volume of Compound Solubility Data to PubChem to Assist Future Drug Discovery Efforts

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February 18th

Sanford-Burnham Scientists Identify Natural Compound that Inhibits Cancer Cell Migration

Molecule found in sea sponges may help control metastasis

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February 12nd

Researchers Identify Mechanism for Frank-Ter Haar Syndrome

Cancer research provides clues to rare, fatal disorder

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February 8th

Dana-Farber and Sanford-Burnham Medical Research Institute License Flu-Targeting Antibodies to Genentech and Roche

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February 1st

New Form of Stem Cell Communication Rescues Diseased Neurons

International Effort Demonstrates Cross-Talk Between Implanted Stem Cells and Diseased Cells in Mouse Model

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January 27th

Secrets of Immunologic Memory

New understanding of CD44 receptor’s role in immune cell survival

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January 26th

T. Denny Sanford Donates $50 Million to Burnham Institute for Medical Research

Institute is renamed Sanford-Burnham Medical Research Institute to honor gift

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January 11st

Team Burnham’s Passion for Science Provides Fuel for the Walt Disney World Marathon

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2009 53 Articles Back to Top
December 21st

How Flu Succeeds

Investigators identify host factors that help multiple influenza strains thrive and could be targeted for new antivirals

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December 16th

Burnham Institute for Medical Research Wins Gold for Green Design

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December 7th

Delivering Medicine Directly into a Tumor

Peptide Delivers Anti-Cancer Compounds to Where They Can Do the Most Good

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December 7th

Burnham Institute for Medical Research Executive Vice President, Dr. Gary F. Raisl, Assumes Chief Financial Officer Duties

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November 16th

Dr. Daniel Kelly, Scientific Director of Burnham at Lake Nona Receives American Heart Association’s 2009 Basic Research Prize

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November 15th

Researchers Find Potential Treatment for Huntington’s Disease

Better understanding of synaptic activity may support “use it or lose it” hypothesis

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November 11st

Mouse Gene Suppresses Alzheimer’s Plaques and Tangles

Protein Reduces Levels of Amyloid Beta and Tau Hyperphosphorylation, Two Hallmarks of Alzheimer’s

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October 20th

Burnham Institute for Medical Research Appoints First Chief Business Officer

 

Dr. Paul Laikind will lead Burnham’s business development team

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October 16th

Burnham Honors Postdoctoral Fellows

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October 9th

Translasome Contains Alpha And Omega of Protein Metabolism

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October 8th

Burnham Institute for Medical Research Expands Scientific Boundaries with Dedication at Lake Nona

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October 8th

University of Florida Formalizes Commitment to Locate Research Facility in Orlando

Lake Nona Medical City Location Facilitates Collaboration with Burnham Institute

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September 21st

Burnham Appoints Michael R. Jackson, Ph.D., Vice President for Drug Discovery & Development

Dr. Jackson will oversee the chemical biology and drug discovery efforts of the Conrad Prebys Center for Chemical Genomics at Burnham

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September 21st

How Proteins Talk to Each Other

Caspase-3 cleaves in unforeseen ways

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September 17th

Burnham Institute for Medical Research and Duke University Sarah W. Stedman Nutrition and Metabolism Center Announce Metabolic Research Collaboration

  • A research partnership that establishes an extension of Duke’s Stedman Center laboratory at Burnham’s Lake Nona campus in Orlando.
  • The collaboration combines the Stedman Center’s metabolite profiling expertise (“metabolomics”) with Burnham’s emerging complementary technologies.
  • Metabolic profiling is used to clarify the basic mechanisms of disease and identify biomarkers for disease diagnosis, drug action and developing individualized treatment plans.
  • The collaboration will initially establish a series of assays for specific metabolites and lead to co-development of new metabolomics technologies.

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September 17th

Building a Complete Metabolic Model

Comprehensive understanding of bacteria could lead to new insights into many organisms

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September 15th

Reactive Oxygen’s Role in Metastasis

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September 14th

New Insights Into Cardiac Aging

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September 11st

When Proteins Change Partners

Competition between proteins maintains cellular balance

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August 27th

The Path to New Antibiotics

Researchers find vulnerable enzyme in pathogens

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August 18th

Scientific Excellence Fuels Burnham’s Growth

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August 17th

Florida Hospital and Burnham Institute Announce New Executive Director and Facility for Clinical Research Institute

The partnership will bridge diabetes and obesity research and treatment

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August 12nd

New Insights into Limb Formation

Novel mouse model reveals role of hyaluronic acid in skeletal growth and could enhance future research

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August 10th

UC Santa Barbara and Burnham Institute for Medical Research Announce Director of New Joint Research Center for Nanomedicine

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August 10th

Burnham Institute for Medical Research Chosen as Comprehensive Center in New National Cancer Institute Chemical Biology Consortium

Drug discovery partnership will translate basic research into new cancer drug candidates

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August 6th

What Makes Stem Cells Tick?

Researchers identify phosphorylated signaling proteins in human embryonic stem cells

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August 5th

Unraveling How Cells Respond to Low Oxygen

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August 3rd

Burnham Institute for Medical Research Faculty Appointed to BioFlorida’s Board of Directors

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July 24th

Protein That Promotes Cancer Cell Growth Identified

Caspase-8 plays an important role in proliferation and invasion of cancer cells

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July 13rd

Burnham Institute for Medical Research Strengthens Research Programs with New Faculty Appointments

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July 6th

Burnham Institute for Medical Research and Magellan BioScience Group, Inc., Announce Drug Discovery Collaboration

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July 6th

Carbohydrate Acts as Tumor Suppressor

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June 25th

MicroRNAs Help Control HIV Life Cycle

Cellular defense mechanism may play role in hiding virus from immune system

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June 15th

Burnham Institute for Medical Research Accelerates Bi-Coastal Expansion at Florida Campus

Appointment of Dr. Timothy Osborne as first program director to lead metabolic signaling and disease research

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June 9th

Embryology Study Offers Clues to Birth Defects

Study reveals mechanism that could combat congenital limb defects like Holt-Oram syndrome

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May 15th

Burnham Campus “Green” Design Fact Sheet

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May 15th

Burnham Scientists Receive Key to New Lake Nona Campus

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April 22nd

Moving Microbes and Microscopes

Burnham Institute for Medical Research begins move to new campus

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April 17th

Burnham Researchers Present at 100th AACR Meeting

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April 13rd

Creating Ideal Neural Cells for Clinical Use

New protocol quickly and efficiently differentiates human embryonic stem cells into committed neural precursor cells

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April 9th

Device Protects Transplanted Pancreatic Cells from the Immune System

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April 8th

Scientists Develop Method for Comprehensive Proteome Analysis

Proof of concept shown with analysis of yeast proteome

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April 3rd

Alzheimer’s Disease Linked to Mitochondrial Damage

Free radicals generated by beta-amyloid proteins lead to mitochondrial fragmentation

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April 2nd

Burnham Institute for Medical Research Demonstrates Commitment to Translational Research with New Faculty Appointment

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March 18th

Protein is Key to Embryonic Stem Cell Differentiation

Burnham scientists identify protein that controls differentiation in human and mouse embryonic stem cells

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February 22nd

Scientists Identify Human Monoclonal Antibodies Effective Against Bird and Seasonal Flu Viruses

Antibodies bind to conserved region of the virus and may offer cross-protection against previous pandemic types and bird and seasonal flu

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February 12nd

Stem Cell Research Uncovers Mechanism for Type 2 Diabetes

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February 1st

The Burnham Buzz, February 2009

Recent developments at Burnham Institute for Medical Research, February 2009

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January 29th

Philanthropist Conrad Prebys Donates $10 Million for Drug Discovery

Burnham Center for Chemical Genomics to be renamed Conrad Prebys Center for Chemical Genomics

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January 13rd

Burnham Announces Assay Development and License Agreement with Johnson & Johnson Pharmaceutical Research & Development, L.L.C.

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January 9th

Digital Communication Technology Helps Clear Path to Personalized Therapies

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January 5th

Burnham Researchers Discover “On Switch” for Cell Death Signaling Mechanism

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January 5th

Burnham Researchers Illuminate Complex Mechanisms That Regulate DNA Damage Control and Replication in the Cell Cycle

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2008 32 Articles Back to Top
December 19th

Peter Preuss Joins Burnham Institute for Medical Research Board

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December 10th

Team Burnham Offers Ten Tips to Stay Healthy During the Holidays

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December 2nd

Burnham and HeadNorth Foundation Join Forces to Advance Spinal Cord Research

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December 1st

Fruit Fly Research May Lead to Better Understanding of Human Heart Disease

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December 1st

The Burnham Buzz

Recent developments at the Burnham Institute for Medical Research, December 2008

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November 25th

Burnham Institute for Medical Research Announces New Faculty Appointments

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November 17th

Dr. Daniel Kelly Receives Distinguished Achievement Award from American Heart Association

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November 12nd

Burnham Institute for Medical Research Elects New Trustees

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October 13rd

Fishman Awards Honor Gifted, Young Burnham Researchers

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October 10th

Burnham Institute for Medical Research Appoints Floridians to Board of Trustees

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October 7th

Burnham Researchers Turn Cancer Friend into Cancer Foe

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October 2nd

What HIV Needs

Identification of human factors may yield novel therapeutic targets for HIV

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September 16th

T. Denny Sanford Donates $30 Million to San Diego Consortium for Regenerative Medicine

Consortium of four research institutions to be renamed Sanford Consortium for Regenerative Medicine

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September 16th

Burnham Researcher Awarded $8 Million Grant

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September 8th

Deborah Robison Joins Burnham Institute for Medical Research as Communications Director for Burnham at Lake Nona

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September 2nd

Burnham Awarded $97.9 Million NIH Grant to Expand Small-Molecule Screening and Discovery Center

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August 21st

Karin Eastham Steps Down as Executive Vice President and Chief Operating Officer of Burnham Institute for Medical Research

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June 30th

Researchers Link Early Stem Cell Mutation to Autism

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June 25th

Nerve Cells Derived from Embryonic Stem Cells and Transplanted into Mice May Lead to Improved Brain Treatments

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June 2nd

Recent developments at Burnham Institute

The Burnham Buzz-June 2008

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May 30th

Potential Therapy Discovered for Hypophosphatasia, a Congenital Form of Rickets

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May 15th

Art Brody Fund Announced at Burnham

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May 12nd

Eric Lofgren Joins Burnham Institute for Medical Research as Vice President, Finance and Chief Financial Officer

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April 25th

Sanford Children’s Health Research Center to be Dedicated in La Jolla

First Faculty Investigators to be Introduced to Boards of Burnham Institute for Medical Research and Sanford Health

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April 17th

Recent developments at the Burnham Institute

The Burnham Buzz-April 2008

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April 4th

T-Cadherin Affects Blood Vessel Growth in Breast Cancer, Hormone from Fat Cells May Play a Role

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April 3rd

RING Finger Protein 5 May Guide Treatment for Muscle Disease in Older Adults

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March 26th

Florida Hospital, Burnham Embark on Groundbreaking Research of the "Diabetic Heart"

The two organizations will also study link between diabetes and obesity

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March 20th

John Reed, M.D., Ph.D, President and CEO of the Burnham Institute for Medical Research, Rings the NASDAQ Opening Bell

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February 20th

Burnham to Host First Research Briefing on Diabetes

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February 6th

Gene Found to Play a Suppressor Role in Skin Cancer Development

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February 5th

Burnham Institute for Medical Research Appoints Daniel P. Kelly, M.D. as Scientific Director for Florida Campus

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2007 28 Articles Back to Top
December 7th

Mechanism by which Signaling Pathways Regulate Growth and Differentiation of Adult Muscle Stem Cells is Revealed

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December 6th

Potentially Safe and Effective Therapy Revealed for Patients with Protein-Losing Enteropathy

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November 18th

Philanthropist Denny Sanford Donates $20 Million for Pediatric Research

Donation Creates Collaboration between Burnham Institute for Medical Research and Sanford Health

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November 8th

The Structural Basis of Familial Hypertrophic Cardiomyopathy is Revealed

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November 7th

Progress Toward New Therapies for Coronary Artery Disease

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October 30th

Rosemary Chicken Protects Your Brain From Free Radicals

Discovery finds mechanism for the herb’s action in ameliorating neurological conditions such as stroke and Alzheimer’s disease

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October 25th

Burnham Institute for Medical Research Professor Yu Yamaguchi Awarded Humanitarian Scientific Achievement Award by MHE

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October 15th

Burnham Institute for Medical Research Appoints Cyril Doucet as Vice President, Operations and Administration for Burnham Florida

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October 1st

Groundbreaking at Lake Nona Marks Breakthrough in Orlando Biotech Industry

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September 26th

Burnham Institute for Medical Research Appoints Andrea Moser as Vice President, Communications

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August 15th

AIDS Interferes with Stem Cells in the Brain

Discovery links mechanism for HIV/AIDS dementia, possibly other neurological disorders, with known cancer "checkpoint" pathway

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June 27th

Donald Bren Foundation Endows President's Chair at Burnham Institute for Medical Research

$2.5 million gift establishes Burnham's first funded chair honoring Dr. John Reed

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June 21st

Burnham Institute for Medical Research Elects New Trustees

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June 8th

Alzheimer's Enzyme Acts as Tumor Suppressor

Burnham study sheds new light on gamma-secretase, drug target for Alzheimer's

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June 5th

CIRM Awards $3.79 Million to Burnham Institute

Funding will support shared research laboratories and expanded facilities for training in human embryonic stem cell research

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June 1st

Burnham Scientist Selected for 57th Lindau Nobel Conference

Nutritional Scientist Lars Bode chosen for once-in-a-lifetime experience

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May 15th

Burnham Institute Names Elizabeth Gianini as Vice President, External Relations, Orlando

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May 14th

Burnham Institute Appoints First Three Recruits to Orlando

"Burnham at Lake Nona, Orlando" to operate in temporary headquarters at Florida's Blood Centers

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April 24th

Karin Eastham Honored with UCSD Athena Pinnacle Award

COO at Burnham Institute for Medical Research earns peer recognition for leadership and mentoring

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April 23rd

NIH Awards $7.39 Million to Burnham Neurobiologists

Funding will support critical understanding of brain development and demyelinating disease

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March 19th

Burnham Institute for Medical Research Appoints Zaugg as Vice President, Business Development

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March 16th

CIRM Awards $6 Million to Burnham Institute

"Comprehensive" grants to support long-range stem cell studies aimed at developing new treatments for heart disease and brain repair

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March 12nd

Stem Cells Act Through Multiple Mechanisms to Benefit Mice with Neurodegenerative Disease

Stem cell study, including the first successful use of human embryonic stem cells in degenerative disease, lays ground work for clinical bridge

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February 26th

Fruit Flies May Pave Way to New Treatments for Age-Related Heart Disease

Humans and flies share a common gene key to heart's pacing

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February 21st

"Bridge" Protein Spurs Deadliest Stages of Breast Cancer

New role for protein yields promising lead for metastasis prevention

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February 16th

CIRM Awards $5.9 Million to Burnham Institute

SEED Grants will launch innovative stem cell research

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January 15th

Team Burnham for Medical Research Races in Phoenix Rock n' Roll Marathon

Runners raise community awareness and funds for Burnham Institute for Medical Research

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January 8th

Homing Nanoparticles Pack Multiple Assault on Tumors

Mimicking platelets' clotting action ensures greater tumor-homing efficacy

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2006 16 Articles Back to Top
December 20th

Researchers Provide Detailed Study of Early Heart Development and Underlying Cause of Congenital Heart Defects

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December 12nd

Burnham Institute for Medical Research Announces Affiliation with University of California, Santa Barbara

Burnham-UCSB home to ”Vascular Mapping Center” founded by Burnham’s Distinguished Professor, Erkki Ruoslahti, M.D., Ph.D.

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November 13rd

Dr. Stefan Riedl Selected as Prestigious “V Foundation Scholar”

V Foundation Scholarship will support cancer drug discovery at Burnham Institute for Medical Research

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October 10th

Burnham Institute Awarded $12.7 Million from NIH to Create One of Nation's Top Neuroscience Research Centers

Collaborative research award will be shared with Salk Institute, Scripps Research Institute, UC San Diego

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September 18th

Experimental Cancer Drugs Counter Muscle Deterioration in Muscular Dystrophy

Normal muscle function restored in dystrophic mice

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August 23rd

Burnham Institute for Medical Research to Establish Major Research Facility in Orlando, Florida

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August 7th

New Insulin Pathway Component may Hold Key to Treating Insulin Resistance, Age-Associated “Metabolic Syndrome”

Fly genetics reveal key workings of Atkins Diet

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July 20th

Researchers from Burnham Institute for Medical Research and UC San Diego Establish Joint Center for Molecular Modeling

$2.1 million grant from National Institutes of Health seeds collaboration to expedite applications from human genome project

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May 26th

Key Stress Protein Linked to Toxicities Responsible for Parkinson’s, Alzheimer’s and Other Neurodegenerative Diseases

Protein Disulphide Isomerase identified as marker for disease, potential drug target

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April 11st

HAP1 Protein Links Circulating Insulin to Brain Circuits That Regulate Feeding Behavior in Mice

Neural Pathway Could Provide Future Drug Targets for Eating Disorders

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March 17th

Four of the Nation's Preeminent Research Institutions Announce Stem Cell Research Alliance

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February 28th

ELISA, at 35 Years, Test is Used for Numerous Applications from Detecting Pregnancies to Analyzing Famous Art

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February 19th

Adult Human Pancreas Stem Cells Transformed into Insulin-Producing Cells

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January 20th

Chief Executive at Burnham Institute for Medical Research Named Among Top Doctors of the Decade

Dr. John C. Reed recognized as the most highly-cited researcher in the field of general biomedicine from 1995-2005 and 8th most highly-cited researcher in clinical medicine

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January 13rd

Kozmetsky Family Gives $1 Million to Support ALS Research at Burnham Institute for Medical Research

Funding will seed stem cell studies on Amyotrophic Lateral Sclerosis

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January 9th

Researchers Discover New Way to Stimulate Brain to Release Antioxidants

Potential drug approach for stroke, Alzheimer's and other neurodegenerative disorders

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2005 23 Articles Back to Top
December 20th

Researchers provide study of early heart development and underlying cause of congenital heart defects

Studies in drosophila genetics inform development of human heart

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December 14th

Burnham Institute for Medical Research to Collaborate on NCI-Funded Task Force to Identify "Molecular Signature" for Prostate Cancer

President & CEO Dr. John Reed to lead project aimed at developing accurate early-stage diagnosis, eliminating unnecessary treatment

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November 28th

Burnham Institute for Medical Research Names Senior Vice President, External Affairs

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November 8th

Stem cell experts at 2nd Annual Christopher Reeve 'Hot Topics' stem Cell Biology Satellite Symposium

Thought leaders gather at 2005 Neuroscience Conference in Washington, DC

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November 1st

Edgar M. Gillenwaters Joins Development Leadership at Burnham Institute for Medical Research

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October 31st

Burnham Institute for Medical Research Announces Appointments

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October 7th

An Antibody Against a Naturally-Occurring Sugar Chain in Colon Halts Progression of Inflammatory Bowel Disease

Ensemble of unusual sugars offers clues to controlling inflammation

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October 3rd

The Burnham Institute to Collaborate in NCI Funded Center of Cancer Nanotechnology Excellence

Distinguished Professor Dr. Erkki Ruoslahti to apply expertise in tumor targeting to develop nano-"homing" devices

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September 30th

The Burnham Institute Board Elects New Members, New Chairman

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September 29th

3-Dimensional Imaging of Motor Proteins Provides New Insights to Molecular Mechanics of Cell Motility, Muscle Contraction

Image of myosin-action interaction revealed in cover story of Molecular Cell

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September 14th

The Burnham Institute Receives Grant from California Institute for Regenerative Medicine

First round of Prop. 71 funding to support training in stem cell research

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September 1st

Cancer Drug Target Chk1 May Also Be Source of Drug Resistance

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

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August 25th

National Foundation for Cancer Research and The Prostate Cancer Foundation Unite with Burnham Institute to Expedite Cancer Drug Discovery

Three-dimensional culture will simulate tumor micro-environment, enable rapid testing for candidate drugs

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August 9th

NIH Selects Burnham Institute for Exploratory Center for Human Embryonic Stem Cell Research

$3M grant will support pilot project, core facilities, and training

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July 29th

New Understanding of Cell Movement May Yield Ways to Brake Cancer’s Spread

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July 6th

Nerve Protector Could Make for New Stroke Treatments - Novel Inhibitor Offsets Neurotoxic Effects of tPA

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June 20th

Anthrax Inhibitors Identified By Burnham Team

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June 16th

National Institites of Health Awards $11.9 M to The Burnham Institute to Establish the San Diego Chemical Library Screening Center

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June 13rd

Burnham Institute Named a Program of Excellence in Nanotechnology by NIH; Awarded $13 M to Mount Nano-Attack on Atherosclerotic Plaque

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May 26th

New Understanding of DNA Repair Processes May Pave Way to Cancer Treatments

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April 19th

United States Scientist Honored with Japan's Highest Award for Global Contributions to Science and Technology

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April 11st

Structure-Building Cell Signals Also May Influence Learning, Memory

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January 13rd

Erkki Ruoslahti of The Burnham Institute Named Recipient of 2005 Japan Prize

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2004 10 Articles Back to Top
December 16th

Inflammation Directs Stem Cells to Injured Tissue

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November 16th

The Burnham Institute's President/CEO Tapped for Prop. 71 Stem-Cell Research Governing Body

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November 9th

A New Target for Control of Obesity

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September 30th

NIH Awards $18.2 Million to The Burnham Institute to Develop Center on Proteolytic Pathways

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August 12nd

Burnham Scientists Discover the Body's Own Defence Against H. Pylori, Cause of Stomach Ulcers and Stomach Cancer

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July 29th

Burnham Stem Cell Project Receives Boost from Coalition for Brain Injury Research

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July 8th

Crystal Structure for Anthrax-Cell Binding Complex Solved

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May 24th

The Burnham Institute Appoints Chief Operating Officer

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May 14th

Stuart A. Lipton, M.D., Ph.D., Honored with Jung Prize for Medicine

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March 15th

Obesity Drug Inhibits Prostate Tumor Growth

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2003 4 Articles Back to Top
December 3rd

Burnham Researchers Discover Molecular Mechanism for Green and Black Tea's Protection Against Cancer

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May 9th

Tiny Protein Prevents Disease-Related Cell Death

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May 2nd

Burnham Scientist Awarded AACR-National Foundation for Cancer Research Professorship in Basic Cancer Research

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April 29th

The Burnham Institute Awarded $500,000 Unrestricted Cancer Research Grant from Bristol-Myers Squibb

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2002 5 Articles Back to Top
October 14th

Erkki Ruoslahti Elected to National Institute of Medicine

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September 10th

Homing Peptides Mounted on Semiconductor Particles Deliver Tiny Payload to Cancerous Tissue in Live Mice

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August 15th

New Enzyme Pathway to Nerve Cell Death Discovered in Stroke and Neurodegenerative Diseases

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June 20th

Peptide Homing to Tumor Lymphatic Tissue Suggests New Cancer Drug Target

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January 30th

Discovery of the Final "Glutamate" Receptor Subunit in the Brain

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2001 1 Articles Back to Top
October 23rd

Crystal Structure of Anthrax Toxin Lethal Factor Informs Its Own Disarmament

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2000 2 Articles Back to Top
June 20th

Researchers Hit on Master Switch to Generate Nerve Cells

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March 31st

John C. Reed Ranks #1 for Hottest Researcher of 1998-1999

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