Our next goal is to look for more genes that interact with Tinman or with other factors that we know are important for the heart.
Dr. Bodmer focuses on the molecular mechanisms of organ formation and the genetic basis of heart development and performance.
Dr. Bodmer earned his Ph.D. in Biochemistry and Neurobiology from the University of Basel, Switzerland, in 1983.
Rolf Bodmer's Research Focus
Cardiovascular Diseases, Heart Disease, Inherited Disorders, Muscular Dystrophy, Metabolic Syndrome, Metabolic Diseases, Obesity, Neurodegenerative and Neuromuscular Diseases, Parkinson's Disease, Cancer
Watch Dr. Bodmer describe his research
The Bodmer Laboratory is interested in the molecular mechanisms of organ formation, how patterns are generated and how cells and tissue types assume their correct fates and functions. The Bodmer lab is pursuing this interest by studying the genetic functions and interactions that specify heart development and maintain heart performance in the Drosophila model, in the hope of elucidating basic principles in organogenesis and functionality.
Cardiac Cell Types
We study the HIF and Notch pathways in various organismal responses to hypoxia. Both of these pathways as well as mechanisms and responses to hypoxia are of high relevance to cancer research.
We are also studying master regulatory networks in how they control metabolism and obesity. These fundamental studies on obesity pathways will also be highly relevant to cancer metabolism.
About Rolf Bodmer
Rolf Bodmer earned his Ph.D. in Biochemistry and Neurobiology from the University of Basel, Switzerland, in 1983. Dr. Bodmer trained as a postdoctoral fellow in Neurobiology at the Albert Einstein College of Medicine in New York, and also studied Molecular Genetics at the University of California, San Francisco. He was appointed Assistant Professor of Biology in 1990 at the University of Michigan. There, he was promoted to Associate Professor of Biology in 1996, and then appointed to Associate Professor of Molecular, Cellular and Developmental Biology in 2001. Dr. Bodmer joined Sanford-Burnham Medical Research Institute in 2003, where he is Professor and Program Director of the Development, Aging, and Regeneration Program.
Adjunct professor, University of California, San Diego
Funding Awards and Collaborative Grants
1 P01 AG033561 "Genetic Analysis of Drosophila Functional Aging"
Honors and Recognition
Ellison Foundation Senior Scholar Award