Brooke Emerling's Research Focus
Research in the Emerling Lab is focused on phosphoinositide signaling, in particular the role of the phosphatidylinositol-5-phosphate 4-kinases (PI5P4Ks) in cancer metabolism. We have shown that the loss of function of the PI5P4K enzymes results in synthetic lethality with p53 loss. Our current work focuses on determining the role of the PI5P4K enzymes in p53 deficient cancers, especially the triple negative breast cancer subgroup where targeted therapies have not been effective.
Brooke Emerling's Bio
Dr. Emerling received her Ph.D. in Molecular and Cellular Biology from Northwestern University and trained as a Postdoctoral Fellow at Harvard Medical School.
Funding Awards and Collaborative Grants
Breast Cancer Research Foundation - AACR Career Development Award for Translational Breast Cancer Research
Mary Kay Foundation Innovative Translational Grant Award
Department of Defense Breast Research Program Breakthrough Award
Honors and Recognition
AACR – Aflac Travel Fellowship Award (2013)
Mastercard Ajay Banga Scientist Award (2013-2016)
NextGen Star – AACR Early-Career Speaker Award (2014)