Sanford Burnham Prebys is uncovering the origins of disease

Fundamental Research
Understanding basic biology and the cause of human disease

Translational Research
Advancing research to clinical breakthroughs for patients through drug discovery and collaborations

Education & Training
Cultivating the next generation of scientists through our graduate school, postdoctoral training programs and fellowships
The Latest News
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Award pays tribute to postdoctoral researcher who succumbed to cancer at age 33.
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Combining MDM2 and BET inhibition produces a "double whammy" effect in acute myeloid leukemia by activating p53 via two different pathways, a new study found.
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Two drugs synergize to unleash anti-tumor effects of p53.
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Immunity
'Immune cop': La Jolla scientists identify the lungs’ sensor that detects virus that causes COVID-19
Sumit Chanda led a study that found the sensor in human lungs that detects SARS-CoV-2, the virus that causes COVID-19. -
Drug Discovery
Meet computational biologist Mallika Iyer
Iyer is studying how proteins “dance,” which could lead to better drugs and a deeper understanding of human health. -
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it’s time to mount an antiviral response.
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Drug Discovery
Scientists uncover protein that empowers antibodies
Discovery may lead to better vaccine strategies and improve treatments for cancer and autoimmune disorders. -
Neuroscience and Aging
Marathon tradition continues for Sanford Burnham Prebys scientist despite pandemic
Jerold Chun is one of only two people to run the Honolulu Marathon every year since 1973. -
Community
Our top 10 discoveries of 2020
Read about our progress in the fight against COVID-19, insights into treating deadly cancers, research that may help children born with a rare condition, and more. -
Neuroscience and Aging
What scientists are learning about COVID-19 and the brain
To learn what scientists know so far about COVID-19 and its effect on the brain, we caught up with Anne Bang, Ph.D., director of Cell Biology at Sanford Burnham Prebys’ Conrad Prebys Center for Chemical Genomics. -
In the News
Astronauts experience these key changes in space that could impact their health, new research shows
"For the first time, we can see the cellular and molecular changes that may underlie the heart conditions seen in astronaut studies," said Karen Ocorr, co-senior author of the study. -
Neuroscience and Aging
Fruit flies reveal new insights into space travel’s effect on the heart
Scientists identify protein production changes in the space flies that weren’t on the radar of heart researchers—opening new avenues for the treatment of heart disease on Earth.
Living History
NCI-Designated Cancer Center
Earning the NCI designation in 1981 — just five years after its modest start in downtown La Jolla — our Cancer Center truly is "the miracle on Torrey Pines Mesa."

Next Generation
ACS awards Sanford Burnham Prebys scientist Research Scholar Grant
The American Cancer Society (ACS) has awarded Brooke Emering, Ph.D., assistant professor in our Cancer, Molecules and Structures Program, a highly competitive Research Scholar Grant.

Living History
Along the road to discovery
It was in 1979 when Eva Engvall asked Erkki Ruoslahti a question that would change their lives forever: "Wouldn't it be great to work in San Diego?"

Next Generation
Graduate student Katja Birker's research doesn't miss a beat
"There is no magic wand to cure congenital heart conditions–we have to do the research."

Calendar
Community Forum
In partnership with the Fleet Science Center
Seminar
Ravid Straussman, M.D., Ph.D., Weizmann Institute of Science
Seminar
Southern California “Breaking News in Stem Cells” Lecture Series
In partnership with UC San Diego Stem Cell Program
Symposium
Community Forum
Hosted by San Diego Independent Scholars
Community Forum
Community Forum
In partnership with the Fleet Science Center
Community Forum
Community Forum
In partnership with the Fleet Science Center
Community Forum
In partnership with the Fleet Science Center
Symposium
COVID-19 matching gift campaign
The power of investing in human health
Dinah Ruch is accelerating our COVID-19 efforts with a generous matching gift that doubles all donations dollar for dollar up to $500,000.

Our Partners in Discovery
We can't do it alone
Our annual Rare Disease Day symposium strengthens the global network of families, physicians and researchers to better understand and fight rare diseases in children.

Our Partners in Discovery
Getting to the finish line faster
Thanks to the philanthropic vision of Stuart and Karen Tanz, a unique collaboration seeks new treatments for diseases such as Alzheimer’s, dementia and Parkinson’s.

Our Partners in Discovery
New hope for autoimmune disease
Our partnership with Lilly—centered around a high degree of interaction—has already produced an immune therapy now in clinical trial.

Our Partners in Discovery
A master class in collaboration
Meet T. Denny Sanford, Conrad Prebys and Malin Burnham: three people who know we're stronger when we work together.
