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Our path starts here

Join us on our journey as we drive scientific research to improve patient treatments for tomorrow.

Cancer

The Institute’s Cancer Center is one of only seven NCI-designated basic cancer research centers in the nation. We couple fundamental biological research with early translational studies to find new, innovative therapies that restore hope to cancer patients and their families.

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Garth Powis D. Phil., headshot
Meet a Scientist

Garth Powis, D. Phil.

Jeanne and Gary Herberger Leadership Chair in Cancer Research

Dr. Powis studies the mechanisms that enable cancer cells to survive stress. 

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Jamey Marth, Ph.D. standing in the lab
Meet a Scientist

Jamey Marth, Ph.D.

Professor, Tumor Microenvironment and Cancer Immunology Program

Dr. Marth's laboratory incorporates biology, engineering, and nanotechnologies to expand biomedical research capabilities.

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Francesca Marassi headshot
Meet a Scientist

Francesca Marassi, Ph.D.

Professor, Cancer Metabolism and Signaling Networks Program

Molecules are the building blocks of cellular life. Knowing their structures is key for understanding the basic mechanisms of...

All Scientists
Immunity

The human immune system is made up of a network of cells, tissues and organs that fight off disease. It can also turn against the body causing autoimmune disorders, such as rheumatoid arthritis, lupus, Crohn’s disease and psoriasis. Increasingly, scientists are learning how to help the body’s immune system to combat cancer. 

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Carl Ware
Meet a Scientist

Carl F. Ware, Ph.D.

Director, Infectious and Inflammatory Diseases Center

Dr. Ware's research is directed at defining the intercellular communication pathways controlling immune responses.

All Scientists
Sumit Chanda profile photo
Meet a Scientist

Sumit Chanda, Ph.D.

Director and Professor, Immunity and Pathogenesis Program

The Chanda lab is interested in unraveling the molecular bases for these complex host-pathogen interactions, which will not only...

All Scientists
Neuroscience and Aging

Diseases associated with aging and development are already a leading cause of death and disability, and their prevalence is rising fast—to give one example, by 2050, the number of Alzheimer’s patients age 65 and older may nearly triple from 5 million to 13.8 million.

Learn more

huaxi hu
Meet a Scientist

Huaxi Xu, Ph.D.

Jeanne and Gary Herberger Leadership Chair in Neuroscience Research

Dr. Xu's research efforts focus on understanding the molecular events that underlie the pathogenesis of Alzheimer's Disease.

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Sanford Children's Health Research Center

Genetic diseases in children are rare, and often incurable. Research insights into the genes and environmental factors that play a role in the development of childhood diseases are leading to better ways to more accurately diagnose, treat and cure children with disease.

Learn more

Yu Yamaguchi headshot
Meet a Scientist

Yu Yamaguchi, M.D., Ph.D.

Professor, Human Genetics Program

Dr. Yamaguchi's studies the role of proteoglycans and glycosaminoglycans in the context of development and human disorders.

All Scientists
Duc Dong, Ph.D., headshot
Meet a Scientist

Duc Dong, Ph.D.

Associate Dean of Admissions, SBP Graduate School

Dr. Dong’s goal is to uncover fundamental insight into basic and biomedical science through the rigorous investigation of the...

All Scientists
Hudson Freeze, Ph.D. headshot
Meet a Scientist

Hudson Freeze, Ph.D.

Director and Professor, Human Genetics Program

Dr. Freeze’s research focuses on the pathology resulting from faulty glycosylation, the process of adding carbohydrate (sugar)...

All Scientists
José Luis Millán, Ph.D. headshot
Meet a Scientist

José Luis Millán, Ph.D.

Professor, Human Genetics Program

Dr. Millán works on understanding the mechanisms that control normal skeletal mineralization and elucidating the...

All Scientists
Cancer

The Institute’s Cancer Center is one of only seven NCI-designated basic cancer research centers in the nation. We couple fundamental biological research with early translational studies to find new, innovative therapies that restore hope to cancer patients and their families.

Learn more

Garth Powis D. Phil., headshot
Meet a Scientist

Garth Powis, D. Phil.

Jeanne and Gary Herberger Leadership Chair in Cancer Research

Dr. Powis studies the mechanisms that enable cancer cells to survive stress. 

All Scientists
Jamey Marth, Ph.D. standing in the lab
Meet a Scientist

Jamey Marth, Ph.D.

Professor, Tumor Microenvironment and Cancer Immunology Program

Dr. Marth's laboratory incorporates biology, engineering, and nanotechnologies to expand biomedical research capabilities.

All Scientists
Francesca Marassi headshot
Meet a Scientist

Francesca Marassi, Ph.D.

Professor, Cancer Metabolism and Signaling Networks Program

Molecules are the building blocks of cellular life. Knowing their structures is key for understanding the basic mechanisms of...

All Scientists
Immunity

The human immune system is made up of a network of cells, tissues and organs that fight off disease. It can also turn against the body causing autoimmune disorders, such as rheumatoid arthritis, lupus, Crohn’s disease and psoriasis. Increasingly, scientists are learning how to help the body’s immune system to combat cancer. 

Learn more

Sumit Chanda profile photo
Meet a Scientist

Sumit Chanda, Ph.D.

Director and Professor, Immunity and Pathogenesis Program

The Chanda lab is interested in unraveling the molecular bases for these complex host-pathogen interactions, which will not only...

All Scientists
Carl Ware
Meet a Scientist

Carl F. Ware, Ph.D.

Director, Infectious and Inflammatory Diseases Center

Dr. Ware's research is directed at defining the intercellular communication pathways controlling immune responses.

All Scientists
Neuroscience and Aging

Diseases associated with aging and development are already a leading cause of death and disability, and their prevalence is rising fast—to give one example, by 2050, the number of Alzheimer’s patients age 65 and older may nearly triple from 5 million to 13.8 million.

Learn more

huaxi hu
Meet a Scientist

Huaxi Xu, Ph.D.

Jeanne and Gary Herberger Leadership Chair in Neuroscience Research

Dr. Xu's research efforts focus on understanding the molecular events that underlie the pathogenesis of Alzheimer's Disease.

All Scientists
Sanford Children's Health Research Center

Genetic diseases in children are rare, and often incurable. Research insights into the genes and environmental factors that play a role in the development of childhood diseases are leading to better ways to more accurately diagnose, treat and cure children with disease.

Learn more

José Luis Millán, Ph.D. headshot
Meet a Scientist

José Luis Millán, Ph.D.

Professor, Human Genetics Program

Dr. Millán works on understanding the mechanisms that control normal skeletal mineralization and elucidating the...

All Scientists
Yu Yamaguchi headshot
Meet a Scientist

Yu Yamaguchi, M.D., Ph.D.

Professor, Human Genetics Program

Dr. Yamaguchi's studies the role of proteoglycans and glycosaminoglycans in the context of development and human disorders.

All Scientists
Duc Dong, Ph.D., headshot
Meet a Scientist

Duc Dong, Ph.D.

Associate Dean of Admissions, SBP Graduate School

Dr. Dong’s goal is to uncover fundamental insight into basic and biomedical science through the rigorous investigation of the...

All Scientists
Hudson Freeze, Ph.D. headshot
Meet a Scientist

Hudson Freeze, Ph.D.

Director and Professor, Human Genetics Program

Dr. Freeze’s research focuses on the pathology resulting from faulty glycosylation, the process of adding carbohydrate (sugar)...

All Scientists

Drug Discovery and Technology

SBP has the talent and resources to accelerate the development of new therapeutics.

Pebys Center robot arm
Prebys Center

Through development and application of modern drug discovery technologies, SBP is uniquely positioned to make next-generation medicines.

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Shared Resources

Our cores provide advanced technology, expertise and instrumentation to investigators.

scientist and assay plate
Other Platforms

SBP innovates and maintains key technologies and partnerships to facilitate research.

Pebys Center robot arm
Prebys Center

Through development and application of modern drug discovery technologies, SBP is uniquely positioned to make next-generation medicines.

slide in microscope
Shared Resources

Our cores provide advanced technology, expertise and instrumentation to investigators.

Pebys Center robot arm
Other Platforms

SBP innovates and maintains key technologies and partnerships to facilitate research.

SBP Pipeline - Current Projects

SBP Pipeline graphic
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Drug discovery projects

News

Marisa Sanchez-SBP-San Diego Union Tribune
In the News
April 19, 2019
Cancer researcher treks to Everest in sister’s memory
The San Diego Union-Tribune
nature communications logo
Paper of the Week
The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration
Alessandra Sacco, Ph.D., Sanford Burnham Prebys
Press Release
April 17, 2019
Boosting Muscle Stem Cells to Treat Muscular Dystrophy and Aging Muscles
Lying within our muscles are stem cells, invisible engines that drive the tissue’s growth and repair. Understanding the signal(s) that direct muscle stem cells...
Fumitoshi Irie, Ph.D., and son-Sanford Burnham Prebys
Beaker Blog April 15, 2019
Autism researcher raising a son with autism shares his story
Twenty years ago, Fumitoshi Irie, Ph.D., was conducting his postdoctoral research in Tokyo when he noticed his nearly 2-year-old son, Koji, exhibiting unusual...
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Nature Communications logo
Paper of the Week
Metascape provides a biologist-oriented resource for the analysis of systems-level datasets
La Jolla Aging Meeting
Beaker Blog April 11, 2019
Sanford Burnham Prebys and Salk co-organize third annual La Jolla Aging Meeting
“Excellent presentation!” “We should connect—we have more samples coming soon.” “Feel free to reach out, we’re looking to partner so I’d love to hear more about...
Read more
FierceBiotech logo
In the News
April 4, 2019
What causes immuno-oncology drug resistance? 2 research teams uncover clues
FierceBiotech
Cosimo Commisso, Ph.D., Sanford Burnham Prebys
Beaker Blog April 4, 2019
AACR selects Sanford Burnham Prebys scientist as NextGen Star
The American Association for Cancer Research (AACR) has named Cosimo Commisso, Ph.D., assistant professor in Sanford Burnham Prebys’ NCI-designated Cancer...
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Sumit Chanda, Ph.D., director of the Immunity and Pathogenesis Program at Sanford Burnham Prebys
Press Release
April 3, 2019
New Metascape Platform Enables Biologists to Unlock Big-Data Insights
For the modern biologist, large-scale OMICs studies—which map all of the genes, proteins, RNA and more that underlie a biological system—are standard tools of...
nature communications logo
Paper of the Week
Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5−/− mice
Ze’ev Ronai, Ph.D., Sanford Burnham Prebys
Press Release
April 2, 2019
Gut Microbiome Directs the Immune System to Fight Cancer
The advent of immune checkpoint inhibitors—which “release the brakes” of the body’s immune system to launch an efficient tumor attack—are a major breakthrough...
The Scientist Logo
In the News
April 1, 2019
Fat Tissue Can Help Cancer Cells Proliferate, Metastasize
The Scientist
5.7m

5.7 million Americans are living with Alzheimer’s. By 2050, this number is projected to rise to nearly 14 million. SBP research hopes to change that.

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