In an effort to find new treatments for COVID-19 that could be made available quickly, researchers searched through FDA-approved drugs to identify candidates that may inhibit SARS-CoV-2 replication. Researchers found that a decades-old anti-leprosy drug exhibits potent antiviral activities against many coronaviruses—including SARS-CoV-2.
In experiments with models of pancreatic cancer, a cyclic peptide called iRGD was found to penetrate tumors via a molecular pathway mediated by β5 integrin. This protein may serve as a useful biomarker, one that could indicate which patients will respond best to iRGD-combination therapy.
Tom Brock started the research that would go on to revolutionize the field of biology – and pave the road to the development of the gold-standard COVID-19 tests used to fight a pandemic – with a question.
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