A new strategy for boosting PD-1 blockers in melanoma

Sanford Burnham Prebys researchers sensitized melanoma to PD-1 blockade by inhibiting a protein called Siah2 in mouse models of the disease.

Study reveals a new approach to enhancing response to immunotherapy in melanoma

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a new way to boost the immune system’s ability to fight cancer.

The secret to a long life? For worms, a cellular recycling protein is key

The discovery could help uncover treatments for age-related conditions, such as Alzheimer’s disease, which are often caused by accumulation of misfolded proteins.