News

Press Release

Scientists shrink pancreatic tumors by starving their cellular “neighbors”

Scientists demonstrated for the first time that blocking “cell drinking,” or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth.

Press Release

Leprosy drug holds promise as at-home treatment for COVID-19

Phase 2 clinical trial could begin immediately for clofazimine, an FDA-approved drug on WHO’s List of Essential Medicines.

In the News

In Pancreatic Cancer, New Biomarker May Predict Benefit of Tumor-Penetrating PeptideIn Pancreatic Cancer, New Biomarker May Predict Benefit of Tumor-Penetrating Peptide

In experiments with models of pancreatic cancer, a cyclic peptide called iRGD was found to penetrate tumors via a molecular pathway mediated by β5 integrin. This protein may serve as a useful biomarker, one that could indicate which patients will respond best to iRGD-combination therapy.

Paper of the Week

Macropinocytosis in Cancer-Associated Fibroblasts is Dependent on CaMKK2/ARHGEF2 Signaling and Functions to Support Tumor and Stromal Cell Fitness

In the News

Evan Snyder named Fellow of the American Institute for Medical and Biological Engineering

Renowned stem cell researcher recognized by his peers for seminal contributions to regenerative medicine.