Jeanne Loring, Ph.D.

Jeanne Loring's Research Focus

Dr. Loring's current research focuses on the molecular basis of pluripotence and differentiation of human embryonic stem cells. Her laboratory studies human embryonic stem cells using gene expression profiling, SNP genotyping, DNA methylation and other high information content approaches to understand how pluripotence is maintained, and how to direct differentiation along specific pathways. 

Jeanne Loring's Bio

Dr. Jeanne Loring has a B.S. in Molecular Biology and a Ph.D. in Developmental Neurobiology. She was on the faculty of the University of California at Davis, and has held research and management positions at biotechnology companies, including Hana Biologics, GenPharm International, Incyte Genomics, and Arcos BioScience. She joined the faculty of Sanford-Burnham Medical Research Institute as a principal investigator in January 2004 and served as Director of the Human Stem Cell Resource and the NIH Human Embryonic Stem Cell Training Course and Co-Director of the institute's NIH Exploratory Center for Human Embryonic Stem Cell Research. In 2007, Dr. Loring joined The Scripps Research Institute as Professor of Developmental Neurobiology. 


Human Genetics Accessory

Publications

Human embryonic stem cells have a unique epigenetic signature.

Bibikova M, Chudin E, Wu B, Zhou L, Garcia EW, Liu Y, Shin S, Plaia TW, Auerbach JM, Arking DE, Gonzalez R, Crook J, Davidson B, Schulz TC, Robins A, Khanna A, Sartipy P, Hyllner J, Vanguri P, Savant-Bhonsale S, Smith AK, Chakravarti A, Maitra A, Rao M, Barker DL, Loring JF, Fan JB

Genome Res 2006 Sep ;16(9):1075-83

Transcriptome coexpression map of human embryonic stem cells.

Li H, Liu Y, Shin S, Sun Y, Loring JF, Mattson MP, Rao MS, Zhan M

BMC Genomics 2006 May 2 ;7:103

Science and law. Intellectual property and human embryonic stem cell research.

Loring JF, Campbell C

Science 2006 Mar 24 ;311(5768):1716-7

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Wind-down of stem-cell institute leaves a void.

Loring JF

Nature 2019 Aug ;572(7768):155

A Report from a Workshop of the International Stem Cell Banking Initiative, Held in Collaboration of Global Alliance for iPSC Therapies and the Harvard Stem Cell Institute, Boston, 2017.

Kim JH, Alderton A, Crook JM, Benvenisty N, Brandsten C, Firpo M, Harrison PW, Kawamata S, Kawase E, Kurtz A, Loring JF, Ludwig T, Man J, Mountford JC, Turner ML, Oh S, da Veiga Pereira L, Pranke P, Sheldon M, Steeg R, Sullivan S, Yaffe M, Zhou Q, Stacey GN

Stem Cells 2019 Sep ;37(9):1130-1135

Reducing <i>Mcl-1</i> gene dosage induces dopaminergic neuronal loss and motor impairments in <i>Park2</i> knockout mice.

Ekholm-Reed S, Baker R, Campos AR, Stouffer D, Henze M, Wolf DA, Loring JF, Thomas EA, Reed SI

Commun Biol 2019 ;2:125

Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair.

Colunga T, Hayworth M, Kreß S, Reynolds DM, Chen L, Nazor KL, Baur J, Singh AM, Loring JF, Metzger M, Dalton S

Cell Rep 2019 Mar 5 ;26(10):2566-2579.e10

Ethical Considerations in the Manufacture, Sale, and Distribution of Genome Editing Technologies.

Sugarman J, Shivakumar S, Rook M, Loring JF, Rehmann-Sutter C, Taupitz J, Reinhard-Rupp J, Hildemann S

Am J Bioeth 2018 Aug ;18(8):3-6

Promoting remyelination through cell transplantation therapies in a model of viral-induced neurodegenerative disease.

Mangale V, McIntyre LL, Walsh CM, Loring JF, Lane TE

Dev Dyn 2019 Jan ;248(1):43-52

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