Niels Volkmann, Ph.D.

Niels Volkmann's Research Focus

Cancer, Cardiovascular Diseases, Infectious Diseases, Inflammatory/Autoimmune Disease

The Volkmann lab seeks to understand biological processes as integrated, hierarchical systems rather than as isolated parts, by developing and applying quantitative analysis tools to link and integrate the scales of atomic-resolution information and imaging of dynamic events in living cells. A key feature of Dr. Volkmann’s research is the highly synergistic collaborations between his laboratory and other research groups (particularly Dr. Hanein’s) that are addressing fundamental questions in cell and cancer biology.

Niels Volkmann's Bio

Niels Volkmann earned his Ph.D. in Biophysics from the University of Hamburg, Germany in 1993, where he also trained as a postdoctoral fellow at the Max Planck Research Unit for Ribosome Structure. He received additional postdoctoral training at Brandeis University at the Rosenstiel Basic Medical Science Research Center and The Keck Center for Cellular Visualization prior to joining Sanford Burnham Prebys in 1999. Dr. Volkmann was promoted to the faculty as Assistant Professor in 2001.



A Versatile High-Vacuum Cryo-transfer System for Cryo-microscopy and Analytics.

Tacke S, Krzyzanek V, Nüsse H, Wepf RA, Klingauf J, Reichelt R

Biophys J 2016 Feb 23 ;110(4):758-65

Three-dimensional structure of Bax-mediated pores in membrane bilayers.

Xu XP, Zhai D, Kim E, Swift M, Reed JC, Volkmann N, Hanein D

Cell Death Dis 2013 Jun 20 ;4:e683

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Biophysical Characterization of a Nanodisc with and without BAX: An Integrative Study Using Molecular Dynamics Simulations and Cryo-EM.

López CA, Swift MF, Xu XP, Hanein D, Volkmann N, Gnanakaran S

Structure 2019 Jun 4 ;27(6):988-999.e4

Electron cryo-tomography of vestibular hair-cell stereocilia.

Metlagel Z, Krey JF, Song J, Swift MF, Tivol WJ, Dumont RA, Thai J, Chang A, Seifikar H, Volkmann N, Hanein D, Barr-Gillespie PG, Auer M

J Struct Biol 2019 May 1 ;206(2):149-155

High Rac1 activity is functionally translated into cytosolic structures with unique nanoscale cytoskeletal architecture.

Marston DJ, Anderson KL, Swift MF, Rougie M, Page C, Hahn KM, Volkmann N, Hanein D

Proc Natl Acad Sci U S A 2019 Jan 22 ;116(4):1267-1272

Does self-organized criticality drive leading edge protrusion?

Anderson KL, Swift MF, Hanein D, Volkmann N

Biophys Rev 2018 Dec ;10(6):1571-1575

Local Tension on Talin in Focal Adhesions Correlates with F-Actin Alignment at the Nanometer Scale.

Kumar A, Anderson KL, Swift MF, Hanein D, Volkmann N, Schwartz MA

Biophys J 2018 Oct 16 ;115(8):1569-1579

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