Niels Volkmann's Research Focus
The Volkmann lab seeks to understand biological processes as integrated, hierarchical systems rather than as isolated parts, by developing and applying quantitative analysis tools to link and integrate the scales of atomic-resolution information and imaging of dynamic events in living cells. A key feature of Dr. Volkmann’s research is the highly synergistic collaborations between his laboratory and other research groups (particularly Dr. Hanein’s) that are addressing fundamental questions in cell and cancer biology.
Niels Volkmann's Bio
Niels Volkmann earned his Ph.D. in Biophysics from the University of Hamburg, Germany in 1993, where he also trained as a postdoctoral fellow at the Max Planck Research Unit for Ribosome Structure. He received additional postdoctoral training at Brandeis University at the Rosenstiel Basic Medical Science Research Center and The Keck Center for Cellular Visualization prior to joining Sanford Burnham Prebys in 1999. Dr. Volkmann was promoted to the faculty as Assistant Professor in 2001.
Tacke S, Krzyzanek V, Nüsse H, Wepf RA, Klingauf J, Reichelt R
Biophys J 2016 Feb 23 ;110(4):758-65
Xu XP, Zhai D, Kim E, Swift M, Reed JC, Volkmann N, Hanein D
Cell Death Dis 2013 Jun 20 ;4:e683
Xu XP, Volkmann N
Arch Biochem Biophys 2015 Sep 1 ;581:49-53
Biophysical Characterization of a Nanodisc with and without BAX: An Integrative Study Using Molecular Dynamics Simulations and Cryo-EM.
López CA, Swift MF, Xu XP, Hanein D, Volkmann N, Gnanakaran S
Structure 2019 Jun 4 ;27(6):988-999.e4
Metlagel Z, Krey JF, Song J, Swift MF, Tivol WJ, Dumont RA, Thai J, Chang A, Seifikar H, Volkmann N, Hanein D, Barr-Gillespie PG, Auer M
J Struct Biol 2019 May 1 ;206(2):149-155
High Rac1 activity is functionally translated into cytosolic structures with unique nanoscale cytoskeletal architecture.
Marston DJ, Anderson KL, Swift MF, Rougie M, Page C, Hahn KM, Volkmann N, Hanein D
Proc Natl Acad Sci U S A 2019 Jan 22 ;116(4):1267-1272
Anderson KL, Swift MF, Hanein D, Volkmann N
Biophys Rev 2018 Dec ;10(6):1571-1575
Kumar A, Anderson KL, Swift MF, Hanein D, Volkmann N, Schwartz MA
Biophys J 2018 Oct 16 ;115(8):1569-1579
Conformational Equilibrium of Human Platelet Integrin Investigated by Three-Dimensional Electron Cryo-Microscopy.
Hanein D, Volkmann N
Subcell Biochem 2018 ;87:353-363