Yasuyuki Kihara, Ph.D.

Yasuyuki Kihara Profile

Yasuyuki Kihara, Ph.D.

Research Assistant Professor

Yasuyuki Kihara's Research Focus

G-Protein Coupled Receptors, Inflammation
  1. Discovery of therapeutic targets in multiple sclerosis (MS) and related neurological disorders.
  2. Systems biology approaches to the study of lipid mediators and G protein-coupled receptors (GPCRs).

Yasuyuki Kihara's Bio

Education

Ph.D., University of Tokyo (JAPAN), Biochemistry and Molecular Biology
M.S., University of Tokyo (JAPAN), Medical Science
B.Pharm., Meiji Pharmaceutical University (JAPAN), Pharmacy

 

Honors and Recognition

HFSP Long-Term Fellowship, 2011-2014 
Japanese Society of Neuroimmunology Award, 2009


pipetting

Publications

Computational Modeling of Competitive Metabolism between ω3- and ω6-Polyunsaturated Fatty Acids in Inflammatory Macrophages.

Gupta S, Kihara Y, Maurya MR, Norris PC, Dennis EA, Subramaniam S

J Phys Chem B 2016 Aug 25 ;120(33):8346-53

Dimethyl fumarate inhibits integrin α4 expression in multiple sclerosis models.

Kihara Y, Groves A, Rivera RR, Chun J

Ann Clin Transl Neurol 2015 Oct ;2(10):978-83

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1.

Chrencik JE, Roth CB, Terakado M, Kurata H, Omi R, Kihara Y, Warshaviak D, Nakade S, Asmar-Rovira G, Mileni M, Mizuno H, Griffith MT, Rodgers C, Han GW, Velasquez J, Chun J, Stevens RC, Hanson MA

Cell 2015 Jun 18 ;161(7):1633-43

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Effects of Myocardial Perfusion Defect on the Frontal QRS-T Angle in Anterior Versus Inferior Myocardial Infarction.

Kurisu S, Nitta K, Sumimoto Y, Ikenaga H, Ishibashi K, Fukuda Y, Kihara Y

Intern Med 2019 Sep 11 ;

JCS 2017/JHFS 2017 Guideline on Diagnosis and Treatment of Acute and Chronic Heart Failure - Digest Version.

Tsutsui H, Isobe M, Ito H, Ito H, Okumura K, Ono M, Kitakaze M, Kinugawa K, Kihara Y, Goto Y, Komuro I, Saiki Y, Saito Y, Sakata Y, Sato N, Sawa Y, Shiose A, Shimizu W, Shimokawa H, Seino Y, Node K, Higo T, Hirayama A, Makaya M, Masuyama T, Murohara T, Momomura SI, Yano M, Yamazaki K, Yamamoto K, Yoshikawa T, Yoshimura M, Akiyama M, Anzai T, Ishihara S, Inomata T, Imamura T, Iwasaki YK, Ohtani T, Onishi K, Kasai T, Kato M, Kawai M, Kinugasa Y, Kinugawa S, Kuratani T, Kobayashi S, Sakata Y, Tanaka A, Toda K, Noda T, Nochioka K, Hatano M, Hidaka T, Fujino T, Makita S, Yamaguchi O, Ikeda U, Kimura T, Kohsaka S, Kosuge M, Yamagishi M, Yamashina A, Japanese Circulation Society and the Japanese Heart Failure Society Joint Working Group.

Circ J 2019 Sep 10 ;

Mutant calreticulin interacts with MPL in the secretion pathway for activation on the cell surface.

Masubuchi N, Araki M, Yang Y, Hayashi E, Imai M, Edahiro Y, Hironaka Y, Mizukami Y, Kihara Y, Takei H, Nudejima M, Koike M, Ohsaka A, Komatsu N

Leukemia 2019 Aug 28 ;

Efficacy and Safety of Ivabradine in Japanese Patients With Chronic Heart Failure - J-SHIFT Study.

Tsutsui H, Momomura SI, Yamashina A, Shimokawa H, Kihara Y, Saito Y, Hagiwara N, Ito H, Yano M, Yamamoto K, Ako J, Inomata T, Sakata Y, Tanaka T, Kawasaki Y, J-SHIFT Study Investigators.

Circ J 2019 Aug 8 ;

Therapeutic response of immunoglobulin 4-related aortitis and pancreatitis demonstrated by diffusion-weighted MRI.

Doi S, Kuroiwa Y, Kusumoto K, Yamashita A, Furukoji E, Tai H, Kihara Y, Hirai T, Asada Y, Imamura T

Radiol Case Rep 2019 Sep ;14(9):1132-1135

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