News

Ligands with different dimeric configurations potently activate the EphA2 receptor and reveal its potential for biased signaling

Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells

Ponesimod inhibits astrocyte-mediated neuroinflammation and protects against cingulum demyelination via S1P1-selective modulation

A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing

Inhibitors of the Hippo Pathway Kinases STK3/MST2 and STK4/MST1 Have Utility for the Treatment of Acute Myeloid Leukemia